The paper presents 96 PνTx vapor phase data values for binary blends of 2,3,3,3-tetrafluoroprop-1-ene (R1234yf) and isobutane (R600a) and 102 PνTx vapor phase data values for binary blends of trans-1,3,3,3-tetrafluoroprop-1-ene (R1234ze(E)) and R600a. The R1234yf/ R600a blends were measured for five isochores (0.0751, 0.0944, 0.1280, 0.1666, 0.1701) m 3 •kg −1 for (303 < T < 383) K for six R600a mole fractions (0.234, 0.400, 0.472, 0.606, 0.772, 0.850) mol•mol −1 . The R1234ze(E)/ R600a blends were measured for four isochores (0.0852, 0.0894, 0.1006, 0.1064) m 3 •kg −1 for (303 < T < 383) K for six R600a mole fractions (0.290, 0.428, 0.516, 0.612, 0.685, 0.755) mol•mol −1 . The data were fitted with a fundamental Helmoltz equation of state (EoS), a Peng−Robinson EoS, and a truncated virial EoS.