A Concept for Magnetic Resonance Visualization of Surgical Textile Implants

Abstract

The integration of SPIOs into the base material combined with IRON is a feasible approach to visualize STI with MRI. This method could help to identify mesh-related problems in time and to reduce the need for surgical revision.

Magnetic resonance visible 3-D funnel meshes for laparoscopic parastomal hernia prevention and treatment

“…STI normally consist of polymers that cannot be depicted using conventional radiological methods. For the first time, meshes can be clearly distinguished from the ambient tissue because superparamagnetic iron oxides are compounded with the polymer of the mesh and this results in magnetic field distortion, which can be detected as signal voids in MRI [4,5]. CT was also considered to visualize iron-marked meshes and even provides better spatial resolution than MRI.…”

“…Therefore, noninvasive reliable diagnostic tools are desirable. Experimental studies report magnetic resonance (MR) visualization of superparamagnetic iron oxide-loaded textile implants for delineation of meshes [4]. The first evaluation in human reports on adequate mesh visualization in open and laparoscopic inguinal hernia repair and introduced a MR protocol with different sequences for visual conspicuity of the implant and evaluation of the surrounding anatomy [5].…”

Conception d’un treillis anti-infectieux et visible en IRM pour la prise en charge chirurgicale des prolapsus génitaux et des hernies abdominales

“…Ces dernières années, quelques équipes de recherche tentent d'incorporer des systèmes au sein de treillis afin de les localiser en IRM, mais à ce jour très peu de résultats sont concluants [24,25]. La stratégie chimique développée au laboratoire a permis de greffer de manière durable un complexant du Gd 3+ (le DTPA), sur le squelette de polymère dégradable (PCL) ou biostable (PAM) pour viser des applications biomédicales temporaires ou permanentes [12,13].…”

A standardized description of graft-containing meshes and recommended steps before the introduction of medical devices for prolapse surgery

“…We anticipate the increased use of added coatings. Nanoparticles or microparticles, for instance, are used as markers or to deliver drugs locally [11,12]. …”

“…Ex vivo, the active properties of explants, such as contractility, can be determined [42]. Imaging studies can theoretically document conformational changes during integration into the host, using either microultrasound, computerized tomography, or magnetic resonance imaging [11,12]. It seems to us that, at this moment, these novel methods, yet promising, are too investigational to make them basic requirements for experimental evaluation prior to clinically launching a product.…”