A comprehensive evaluation of different risk-assessment models to predict 30-day postoperative complications in gynaecologic patients undergoing surgery under an Enhanced Surgical Recovery Programme (ESRP)

Abstract

Objectives: The application of high oxygen concentration during the perioperative period is controversial. A recent meta-analysis concludes that it decreases the risk of surgical site infection (SSI) after colon surgery. Nevertheless, some authors suggest an increase in long-term mortality. The goal of the study was to analyze if perioperative hyperoxia therapy decreases the incidence of infectious complications after elective colon surgery without increasing long-term mortality. Methods: We performed a retrospective analysis on 223 patients who underwent elective colorectal surgery between 2011 and 2013. Patients were divided into 2 groups. Hyperoxia group received perioperative (intraoperative + 2 hours postoperative) FiO 2 80%. Control group received standard perioperative FiO 2 (50%). SSI was recorded from a prospective collected surgeon's database. We realised a follow-up study of long-term mortality of the patients until January 2015. Demographic, intraoperative data and cancer stage were also recorded. Statistical analysis: Quantitative data expressed as mean±standard deviation.