A comparison of ST elevation versus non-ST elevation myocardial infarction outcomes in a large registry database

Poloński, Lech; Gąsior, Mariusz; Gierlotka, Marek; Osadnik, Tadeusz; Kalarus, Zbigniew; Trusz‐Gluza, Maria; Zembala, Marian; Wilczek, Krzysztof; Lekston, Andrzej; Zdrojewski, Tomasz; Tendera, Michał

doi:10.1016/j.ijcard.2010.07.008

Cited by 87 publications

(67 citation statements)

References 30 publications

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“…Our in-hospital mortality rates for STEMI are comparable to the OPERA Registry and Swiss registry of acute coronary syndrome (4.6% and 4.8% for STEMI, respectively) [16,17], but significantly lower than in the PL-ACS Registry Pilot Group, which revealed an in-hospital mortality rate of 11.6% for STEMI and 8.7% for NSTEMI [18]. We also noted that patients with NSTEMI or UA had a more favourable outcome than patients with STEMI, as frequently reported previ-pital mortality, were most commonly pretreated with aspirin, statins and/or beta-blockers on admission.…”

Section: Discussionsupporting

confidence: 64%

Current outcome of acute coronary syndromes: data from the Zurich-Acute Coronary Syndrome (Z-ACS)-Registry

2013

Cardiovasc Med

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Section: Discussionsupporting

confidence: 64%

Current outcome of acute coronary syndromes: data from the Zurich-Acute Coronary Syndrome (Z-ACS)-Registry

2013

Cardiovasc Med

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“…Although in-hospital mortality is higher in patients with ST-segment elevation myocardial infarction (STEMI) than among those with NSTEMI, long-term follow-up showed worse outcomes in NSTEMI patients [1,2]. It is important to determine factors worsening prognosis in this constantly increasing group of patients.…”

Section: Introductionmentioning

confidence: 99%

Post-procedural TIMI flow grade 2 is not associated with improved prognosis in patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary revascularization (PL-ACS registry)

et al. 2016

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Background: The impact of final Thrombolysis in Myocardial Infarction (TIMI) flow in the infarct-related artery (IRA) on outcomes in non-ST-segment elevation myocardial infarction (NSTEMI) patients treated with percutaneous coronary intervention (PCI) is unknown.This study aimed to evaluate the impact of post-procedural TIMI flow in IRA on outcomes in NSTEMI patients undergoing percutaneous coronary revascularization. 3.26%; 2: 61, 2.20%; 3: 2,616, 94.54%). Methods: We analyzed 2,767 patients with first NSTEMI from the Polish Registry of Acute Coronary Syndromes (PL-ACS) who underwent PCI. The patients were divided according to Results:The following mortality values were obtained in TIMI 0-1, 2, and 3 groups, respectively: in-hospital, 12.22%, 13.11%, 1.72% (p < 0.0001); 1-month, 13.33%, 13.11%, 3.44% (p < 0.0001); 12-month, 15.56%, 16.39%, 6.50% (p < 0.0001); 36-month, 25.56%, 21.31%, 13.91% (p = 0.0007) . Mortality rates in patients with final TIMI 0-1 and 2 were not significantly different. Optimal TIMI 3 was independently associated with baseline TIMI 2-3 (OR ±

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“…3,5 In patients with cardiovascular disease, the prevalence of OSA ranges between 47 and 83%. 6 Because percutaneous coronary intervention has been considered a sign of poor long-term prognosis of acute coronary syndrome, 7 optimizing related diseases in these patients is critical.…”

Section: Introductionmentioning

confidence: 99%

The Relationship Between Obstructive Sleep Apnea Hypopnea Syndrome and Inflammatory Markers and Quality of Life in Subjects With Acute Coronary Syndrome

Yuan

Wang

et al. 2016

Respir Care

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BACKGROUND: The objective of this work was to examine the relationship between obstructive sleep apnea (OSA) and inflammatory markers and quality of life in patients with acute coronary syndrome, especially undergoing percutaneous coronary intervention. METHODS: One hundred eighteen subjects were admitted with acute coronary syndrome over 1 y who had symptoms of OSA and positive polysomnography on admission. Of these subjects, 53 underwent primary percutaneous coronary intervention during their admission, and 65 had medical management. We then compared inflammatory markers by OSA status. We also assessed cardiac symptoms using the Seattle Angina Questionnaire and sleep symptoms using the Epworth Sleepiness Scale. RESULTS: Subjects in the percutaneous coronary intervention group had a higher oxygen desaturation index (ODI) (P ‫؍‬ .02) and apnea-hypopnea index (AHI) (P ‫؍‬ .048) compared with those in the medical management group. In percutaneous coronary intervention subjects, the moderate-severe OSA group (AHI > 15/h) had a higher hematocrit (P ‫؍‬ .047), homocysteine (P ‫؍‬ .01), and highsensitivity C-reactive protein (P ‫؍‬ .045) compared with those with no or mild OSA (AHI < 15/h). There was a significant correlation between high-sensitivity C-reactive protein and both AHI (r ‫؍‬ 0.46, P ‫؍‬ .001) and ODI (r ‫؍‬ 0.47, P < .001). Those with moderate-severe OSA had higher Epworth Sleepiness Scale (P ‫؍‬ .002), greater physical limitation (P ‫؍‬ .01), and lower treatment satisfaction and disease perception (P ‫؍‬ .007), as judged by subscales of the Seattle Angina Questionnaire, compared with those with no or mild OSA. Finally, subjects undergoing percutaneous coronary intervention with lower AHI (r ‫؍‬ 0.48, P < .001) and ODI (r ‫؍‬ 0.49, P < .001) reported higher treatment satisfaction. CONCLUSIONS: Subjects with acute coronary syndrome undergoing percutaneous coronary intervention who had moderate-severe OSA showed higher levels of inflammatory mediators and lower treatment satisfaction and disease perception. These factors may increase the risk of adverse sequelae by increasing the systemic inflammatory response.

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A comparison of ST elevation versus non-ST elevation myocardial infarction outcomes in a large registry database

Cited by 87 publications

References 30 publications

Current outcome of acute coronary syndromes: data from the Zurich-Acute Coronary Syndrome (Z-ACS)-Registry

Current outcome of acute coronary syndromes: data from the Zurich-Acute Coronary Syndrome (Z-ACS)-Registry

Post-procedural TIMI flow grade 2 is not associated with improved prognosis in patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary revascularization (PL-ACS registry)

The Relationship Between Obstructive Sleep Apnea Hypopnea Syndrome and Inflammatory Markers and Quality of Life in Subjects With Acute Coronary Syndrome

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