A comparison of self‐reported quality of life for an Australian haemodialysis and haemodiafiltration cohort

Hill, Kathleen; Kim, Susan; Crail, Susan; Elias, Tony J; Whittington, Tiffany

doi:10.1111/nep.12832

Cited by 6 publications

(3 citation statements)

References 22 publications

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“…The CONvective TRAnsport STudy (CONTRAST) study did not find a significant difference between the two treatment modalities through the Kidney Disease Quality of Life 36-Item short form survey (KDQoL SF-36) questionnaire. 18 Small cross-over studies comparing HD to HDF have shown various results: some did not find any significant difference in quality of life between groups, 19 , 20 whereas others found HDF to be beneficial in regard to “bodily pain” and “role limitations due to emotional functioning,” 15 and to be associated with better score on KDQoL SF-36 compared with HD. 21 More recently, Smith et al, 22 in a randomized, single-blind, cross-over study comparing high-flux HD with HDF, reported similar recovery time and quality of life scores, through KDQoL SF between groups.…”

Section: Discussionmentioning

confidence: 99%

Quality of Life and Hemodynamic Effects of Switching From Hemodialysis to Hemodiafiltration: A Canadian Controlled Cohort Study

Éthier

Nevis

Suri

2021

Can J Kidney Health Dis

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Background: Recent randomized clinical trials have demonstrated beneficial effects of hemodiafiltration (HDF) compared with hemodialysis (HD) on mortality and hemodynamic stability. Data on quality of life in HDF compared with HD is limited. Objective: This study aimed to determine whether patients receiving HD experience improvements in quality of life, hemodynamic and laboratory parameters after switching to HDF. Design: Observational controlled cohort study. Setting & Patients: Adult patients receiving maintenance dialysis were followed for 3 months both before and after transfer to a new unit, where they received HDF. Prior to transfer, control patients were already treated by HDF. Methods: Quality of life at baseline and follow-up was measured using the validated minutes to recovery (MR) question. Dialysis data were collected for 3 consecutive sessions monthly; laboratory values were collected monthly. Wilcoxon signed rank test and repeated measures analysis of covariance were used to evaluate pre/post transfer changes and quantile regression to identify predictors of change in recovery time. Results: Of 227 patients, 82 died, were transplanted, were hospitalized or did not transfer, leaving 123 subjects and 22 controls for analysis. MR did not improve with switching to HDF, although patients with MR > 60 min before transfer experienced a significant decrease in their MR, compared with controls. There was no improvement in intradialytic hypotension with HDF. There were no differences in laboratory values before vs after switch. Limitations: Nonrandomized single-center study, including only small numbers of patients and covering a short follow-up period; hemodynamic values only evaluated over 1 week per month; residual kidney function not recorded. Conclusions: In this Canadian experience of HDF, patients remained stable with respect to several laboratory and dialysis related parameters. Switch to HDF was associated with substantially reduced recovery time in patients with MR > 60 minutes at baseline.

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Section: Discussionmentioning

confidence: 99%

Quality of Life and Hemodynamic Effects of Switching From Hemodialysis to Hemodiafiltration: A Canadian Controlled Cohort Study

Éthier

Nevis

Suri

2021

Can J Kidney Health Dis

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“…Self-reported quality of life (QoL) Measuring QoL was highly subjective because it depended on self-reported answers [27]. QoL contained multiple domains [1], but scholars agreed that a one-dimensional measure was adequate to represent it for large-scale surveys [28].…”

Section: Methodsmentioning

confidence: 99%

Classifying and Characterizing the Development of Self-Reported Quality of Life Among the Chinese Elderly: A Twelve-Year Longitudinal Study

Huang

Zhang

Fang

et al. 2021

Preprint

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Background To promote healthy aging, the information about the development of quality of life (QoL) is of great importance for health researchers and policymakers. Up to now, the longitudinal explorations of the heterogeneity in the change of QoL under the Chinese context were largely limited. The current study aimed to identify potential different development patterns of QoL and the influential factors using a large, longitudinal, and nationally representative sample of the Chinese elderly. Methods We adopted a five-wave longitudinal dataset from the Chinese Longitudinal Healthy Longevity Survey (CLHLS), and a total of 1,645 elderly aged 65 and over were obtained. QoL was measured using a self-report item during the longitudinal process. We utilized the conditional growth mixture model (GMM) with time-invariant covariates to explore various development patterns and associated factors. Results Three subgroups with distinct trajectories of self-reported QoL were identified: the High-level Steady Group (17.08%), the Mid-level Steady Group (63.10%), and the Low-level Growth Group (19.82%). Results also indicated that several factors predicted distinct trajectories of self-reported QoL. Those elderly who received enough financial resources, had adequate nutrition, did not exhibit any disability, engaged in leisure activities, and did less physical labor or housework at the baseline were more likely to report a higher level of QoL over time. Conclusions There existed three development patterns of self-reported QoL among the Chinese elderly, and these subgroups differed in several baseline factors. These findings provided valuable implications for the maintenance and improvement of QoL among the Chinese elderly.

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“…Generally, these data, however, often lose significance once selection bias of patients chosen for HDF therapy are removed (Locatelli et al 2017). There is evidence from a number of individual studies that HDF can be beneficial for individual patients (Davenport et al 2010, Oates et al 2011, Maduell et al 2013, Dey et al 2015, Hill et al 2017 and for this reason many units have made the therapy available to increasing numbers of HD patients in recent years. Most commonly reported benefits of HDF in these studies include; improved haemodynamic stability during treatment, improved blood pressure control, improved dialysis clearance (Kt/V), improved phosphate control (sometime with ability to reduce dose of phosphate binders) and often qualitative indications of improved quality of life.…”

Section: Hdf Evidence Basementioning

confidence: 99%

A review of the evidence for the use of haemodiafiltration

Dainton

2017

Journal of Kidney Care

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Most patients with end stage renal disease (ESRD) are supported with maintenance haemodialysis (HD) and this has been the case for many years. Recent improvements in water quality have led to the increased use of high-flux HD and more recently of online-haemodiafiltration (HDF). HDF has been promoted by some clinicians and by renal industry as potentially offering improved clinical and quality of life outcomes for patients over conventional HD. However, despite such benefits making theoretical sense very few studies of the use of HDF as compared to HD (especially high-flux HD) have been able to demonstrate any significant benefit for the therapy. This article reviews the most recent research that has compared HDF and HD and has identified that the evidence for the benefit of HDF remains elusive. This article, therefore, concludes that there is currently still not sufficient evidence from the research to support the contention that HDF confers benefits to patients over conventional HD and thereby no compelling evidence to justify its widespread use as a preferred form of treatment.

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A comparison of self‐reported quality of life for an Australian haemodialysis and haemodiafiltration cohort

Abstract: This study has demonstrated that younger age and comorbid diabetes were responsible for a statistically significant reduction in quality of life, and HDF did not confer any advantage.

Cited by 6 publications

References 22 publications

Quality of Life and Hemodynamic Effects of Switching From Hemodialysis to Hemodiafiltration: A Canadian Controlled Cohort Study

Quality of Life and Hemodynamic Effects of Switching From Hemodialysis to Hemodiafiltration: A Canadian Controlled Cohort Study

Classifying and Characterizing the Development of Self-Reported Quality of Life Among the Chinese Elderly: A Twelve-Year Longitudinal Study

A review of the evidence for the use of haemodiafiltration

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