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Cited by 25 publications
(30 citation statements)
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“…On the contrary, all the most recent meta-analyses (table 2) revealed a significant increase of risk for anastomotic dehiscences after OBC. Indeed, this observation is in accordance with some experimental studies indicating histological damage and impairment of anastomotic healing after bowel preparation prior to colonic resection [38,39,40]. But even the rate of surgical infectious complications such as wound infections, abscesses and peritonitis could not be lowered by preoperative OBC according to the highest level of evidence in the literature.…”
Section: Resultssupporting
confidence: 86%
“…On the contrary, all the most recent meta-analyses (table 2) revealed a significant increase of risk for anastomotic dehiscences after OBC. Indeed, this observation is in accordance with some experimental studies indicating histological damage and impairment of anastomotic healing after bowel preparation prior to colonic resection [38,39,40]. But even the rate of surgical infectious complications such as wound infections, abscesses and peritonitis could not be lowered by preoperative OBC according to the highest level of evidence in the literature.…”
Section: Resultssupporting
confidence: 86%
“…In one experimental study, PEG and lactated Ringer's solutions for WBI were found to be safer than saline solution, because they led to less histopathological changes on the mucosa of the whole gastrointestinal tract and in liver specimens. Thus, the authors considered saline solution as inadvisable for mechanical bowel preparation according to histopathological studies [11]. In contrast, we obtained the best results with saline compared to the other study groups during the traditional method.…”
Section: Discussionmentioning
confidence: 62%
“…The specimens were evaluated for the presence of congestion, edema and inflammation in the cecal wall. Samples were graded as follows [11]: grade 0 = cecal wall with normal histological findings; grade 1 = mucosal involvement only; grade 3 = mucosal and submucosal involvement, and grade 4 = involvement extending beyond submucosa.…”
Section: Histopathological Analysismentioning
confidence: 99%
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“…Moreover, some studies indicated that polyethylene glycol (PEG) and other agents used for bowel preparation may have negative effects on the histopathologic constituency of colonic tissue [18][19][20][21]. Little is known about the effect of PEG on the mechanical properties of the colon and on anastomotic healing.…”
Section: Introductionmentioning
confidence: 99%