volume 41, issue 2, P153-161 2013
DOI: 10.1016/j.jcms.2012.07.003
View full text
Patrick H. Warnke, Andreas Humpe, Dirk Strunk, Sebastien Stephens, Frauke Warnke, Joerg Wiltfang, Katharina Schallmoser, Mohammad Alamein, Robert Bourke, Peter Heiner, Qin Liu

Abstract: The transplantation of human stem cells seeded on biomaterials holds promise for many clinical applications in cranio-maxillo-facial tissue engineering and regenerative medicine. However, stem cell propagation necessary to produce sufficient cell numbers currently utilizes fetal calf serum (FCS) as a growth supplement which may subsequently transmit animal pathogens. Human platelet lysate (HPL) could potentially be utilized to produce clinical-grade stem cell-loaded biomaterials as an appropriate FCS substitut…

expand abstract