A Clinical Overview of a Retrospective Study About Adult Intussusceptions: Focusing on Discrepancies Among Previous Studies

Abstract

This study was to determine clinical entity of adult intussusception, focusing on discrepancies among previous studies and to retrospectively investigate the factors associated with malignancy and survival for 10 years. In our study, 3.7% (N = 42) of intussusception were adults. The most common symptom was acute abdominal pain (64.3%). Enteric, ileocolic, ileocecal, and colocolic intussusception included 52.4, 9.5, 14.3, and 23.8% of patients, respectively. Two patients (9.1%) with enteric (N = 22), no patient with ileocolic (N = 4), three patients (50%) with ileocecal (N = 6), and five patients (50%) with colocolic (N = 10) intussusception were malignant. The factor associated with malignancy was only chronic abdominal pain without acute abdominal pain (P = 0.018) and the absence of fever and ileocecal intussusception were associated with survival (P = 0.010, 0.009). In our study, the most common symptom was acute abdominal pain, and enteric intussusception was the most common type. The difference in clinical presentation and location of intussusception might have resulted from small number of cases or selection of cases.

Small Bowel Cavernous Hemangioma Complicated with Intussusception: Report of an Extremely Rare Case and Review of Literature

“…Primary or idiopathic adult intussusception accounts for only 10 % of cases and is more likely to develop in the small intestine. Up to 90 % of occurrences in adults have a leading point, which is defined as a welldefinable pathological abnormality [6].…”

Adult ileocolic intussusception secondary to infectious enterocolitis: anecdotic cause of an uncommon condition

“…Ileocolic intussusception associated to Salmonella typhimurium infection has been previously reported on only one occasion, constituting an extremely uncommon occurrence [4]. Ileocolic intussusception accounts for less than 10% of all adult intussusceptions, being a rather uncommon condition [3].We discuss a case of ileocolic intussusception associated with infectious enterocolitis caused by Salmonella enteritidis.…”

“…The exact mechanism that precipitates intussusception is still unknown, but it is believed that any lesion in the bowel wall or irritant contents within the bowel lumen may alter the normal peristaltic pattern, starting the process of invagination [1]. Adult intussusception is rare, accounting for only 5% or less of all reported cases [2,3]. In contrast to pediatric intussusception, 90% of adult intussusceptions will have a leading point, usually a malign neoplasm, while the remaining 10% are considered idiopathic [2].…”

Giant Ileo-cecal Lipoma Causing Intussusception in an Adult: A Case Report and a Review of Literature

“…It is usually a condition of the pediatric population and the adult form is regarded as a rare condition that constitutes approximately 5% of all intussusceptions and it accounts for 1% of all adult intestinal obstructions. 1 Adult intussusceptions are generally the result of benign masses such as various polyps, adenomas and lipomas but malignant lesions such as adenocarcinoma of the bowel are nevertheless may be etiological factors. 2 Most studies reported that 60-80% of enteric intussusceptions were benign and 50-65% of colonic intussusceptions were malignant.…”

“…2 Most studies reported that 60-80% of enteric intussusceptions were benign and 50-65% of colonic intussusceptions were malignant. 1 Lipoma of the bowel wall is an infrequent entity and it may very well be a ground for adult type intussusception. They are usually clinically silent and may end up developing intussusceptions when they reach to several centimetres in size.…”