A Clinical Appraisal of the Dialysis Index

Importance of dialysis adequacy in mortality and morbidity of Chinese CAPD patients

“…The higher serum albumin level was icy might not be ideal, it provided a special opportunity associated with better technique survival and fewer days Our study further confirmed the intriguing observaof hospitalization. The findings were similar with other tion that Asian CAPD patients enjoyed a better outcome studies in Caucasian CAPD patients [5, [19][20][21]. The ef-[6, 7,22].…”

“…Two-year patient survival was 83% in our fects of diabetes on patient survival and CVD on hospistudy (with an average Kt/V of 1.75) versus 78% in the talization also shared much similarity with the Caucasian CANUSA study (average Kt/V, 2.1) [5]. Extrapolation series [5,19]. It was important to note that in addition to of our adequacy and survival data found that for a total Kt/V and C Cr , residual GFR appeared as an independent Kt/V of 1.9, the expected two-year patient survival was predictor of patient survival.…”

“…sian population [2-5, [19][20][21]. However, the relationship Over half of the patients were never hospitalized duris less clear in Asians.…”

“…Recent studies suggested that this assumption [5,29]. Recently, the difference in the background popumight not be valid [19,28].…”

Middle Molecules Re-Examined

“…While many were critical of the terminology 'square meter hour hypothesis' because it failed to encompass important variables such as dialyzer efficiency, membrane permeability and variation in the generation rales for toxic solutes, the importance of the alterations in dialysis prescription as an in vestigative tool was quickly appreciated and exploited by numerous investigators. Cited by way of example is the work of Ginn et al [14], Ratazzi et al [28], Rosenzwelg et al [29], and Teehan et al [35]. Identification of the impor tance of these treatment variables plus the overriding importance of residual renal func tion in weekly clearance figures for middle molecules [2] has helped explain the reports of neuropathy occurring after initiating main tenance dialysis [1,4,21].…”