A clinical and mycological study of onychomycosis in HIV infection

Surjushe, Amar; Kamath, Ratnakar; Oberai, Chetan; Saple, D. G.; Thakre, Minal; Dharmshale, Sujata; Gohil, Aruna

doi:10.4103/0378-6323.37057

Cited by 55 publications

(43 citation statements)

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“…The prevalence of onychomycosis was similar to the other studies, in the range of 15-40%. 11 However, the type of nail involvement was at odds with earlier studies in which proximal subungual onychomycosis (PSO) 12 and DLSO constituted the predominant variety. 13 Proximal subungual onychomycosis which is pathognomonic of HIV infection was not present in any of the patients, thus underlying its rarity in the Indian setting.…”

Section: Interesting Findings Of the Studycontrasting

confidence: 51%

Cutaneous manifestations of HIV—a detailed study of morphological variants, markers of advanced disease, and the changing spectrum

Vasudevan¹,

Sagar

Bahal

et al. 2012

Medical Journal Armed Forces India

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. All HIV-positive patients attending outpatient departments (OPDs) and admitted as inpatients during the above period were included in the study. Initial screening for HIV was done by the rapid test and, if positive, was confirmed by two different types of enzyme-linked immunosorbent assay (ELISA). Patients already on anti-retroviral therapy (ART) were not included. Age, weight, probable time of first high-risk behaviour and CD4+ counts were noted. A complete medical history and physical examination of patients was carried out for optimal evaluation and diagnosis of dermatological and venereological lesions. The diagnosis was based on clinical criteria in most of the cases. Appropriate laboratory tests like scraping for fungus/candida, culture, skin biopsy, Cutaneous manifestations of HIV-a detailed study of morphological variants, markers of advanced disease, and the changing spectrum RESULTSInfections were the most common group of mucocutaneous manifestations, while onychomycosis was the commonly observed individual manifestation. A different set of cutaneous markers for advanced HIV disease was observed and new parameters for therapy were also arrived at. MJAFI 2012;68:20-27 CONCLUSION

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Section: Interesting Findings Of the Studycontrasting

confidence: 51%

Cutaneous manifestations of HIV—a detailed study of morphological variants, markers of advanced disease, and the changing spectrum

Vasudevan¹,

Sagar

Bahal

et al. 2012

Medical Journal Armed Forces India

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“…hydrolase, keratinase and cysteine dioxygenase) has been reported. [24] The T. mentagrophyte being more active destroyer than T. rubrum. [21] Thus, the species identification is of importance to a clinician for the effective management and prognosis of the disease while treating Onychomycosis.…”

Section: Discussionmentioning

confidence: 99%

Clinico-Mycological Profile of Onychomycosis in a Tertiary Care Centre of Tripura

Debbarma¹,

Barman²,

Majumdar³

2016

jemds

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BACKGROUND AND OBJECTIVESOnychomycosis is an underreported progressive, recurrent fungal nail infection of human beings. So far, there is no documented study regarding causative agents of Onychomycosis in Tripura. In view of this, the study was conducted in a tertiary healthcare centre of Tripura aiming laboratory diagnosis of Onychomycosis with objectives of, (1) Epidemiology of Onychomycosis among the study subjects, (2) Profiling of aetiological agents.

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“…2 In Indian reports the commonest non-dermatophyte mould reported is A.niger. 21,9 In our study, M. nanum was the unusual isolate from one patient. She was a 50 years female working as staff nurse.…”

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confidence: 51%

A clinico-mycological study of onychomycosis at a tertiary care center

et al. 2017

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Background: Onychomycosis continues to be worldwide problem constituting a large bulk of cases attending the dermatology outpatient department. Fungal infections of nails have been partly studied, because it has been considered more of a cosmetic problem than a health problem. Although not life threatening, onychomycosis may have significant clinical consequences such as secondary bacterial infection, chronicity, therapeutic difficulties and disfigurement, in addition to serving as reservoir of infection. Aims and Objectives: 1) To find out the prevalence, etiology and clinico-mycological correlation of onychomychosis among clinically suspected cases. 2) To compare the microscopy findings using potassium hydroxide (KOH) preparation with potassium hydroxide-dimethyl sulfoxide (KOH-DMSO/ DMSO) preparation. 3) To compare demographic and clinical data in onychomycosis and fungus negative groups. Material and Methods: The study was conducted from October 2011 to October 2013, in the department of Microbiology of a tertiary care hospital in Mumbai, including 204 patients clinically suspected of onychomycosis. Nail scrapings were collected depending upon site, type of nail involvement and subjected for microscopic examination using 20% KOH and KOH DMSO (10-40%), followed by fungal culture. Results: Out of 204 patients, 78 (38.2%) were diagnosed having onychomycosis, 72 (92.3%) patients were positive by direct microscopy and 45 (57.7%) by culture. DMSO preparation offered a faster clearing of background but in KOH preparation fungal morphology was better maintained even after 24 hours. In culture positive cases, isolation of dermatophytes was most common (42.2%), followed by Candida species (31.1%) and nondermatophytes (26.7%). Conclusion: This concludes that laboratory diagnosis of onychomycosis is essential as many conditions of nail mimic onychomycosis. Though commonest causative agents of onychomycosis are dermatophytes, number of cases caused by Candida species and nondermatophytesare on the rise.

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A clinical and mycological study of onychomycosis in HIV infection

Abstract: Total dystrophic onychomycosis was the most common clinical type and NDM were the predominant causative organisms.

Cited by 55 publications

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Cutaneous manifestations of HIV—a detailed study of morphological variants, markers of advanced disease, and the changing spectrum

Cutaneous manifestations of HIV—a detailed study of morphological variants, markers of advanced disease, and the changing spectrum

Clinico-Mycological Profile of Onychomycosis in a Tertiary Care Centre of Tripura

A clinico-mycological study of onychomycosis at a tertiary care center

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