A chip-integrated highly variable thermal flow rate sensor

Hoera, Christian; Skadell, Mirjam M.; Pfeiffer, Simon A.; Pahl, Maik; Shu, Zhe; Beckert, Erik; Belder, Detlev

doi:10.1016/j.snb.2015.11.009

Cited by 22 publications

(12 citation statements)

References 60 publications

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“…Fig. 7 shows the measured FSR as a function of pressure as well as the bubble diameter calculated from equation (3). It can be observed that the FSR increases linearly while the diameter of the bubble decreases with the inverse of pressure.…”

Section: Resultsmentioning

confidence: 97%

“…A general objective of science and technology is the reduction in size, number of components and production costs of measurement systems. Optics takes great relevance in microfluidics since it offers new methods for matter manipulation [1,2] and for the characterization of thermodynamic and mechanical properties of fluids [3], which leads to smaller optical devices with low or nil operating voltages, no moving mechanical parts, additional functionality and great potential in performance. Optical fibers are used in fluidics because of their small size, high sensitivity, and remote sensing capabilities [4]; furthermore, fibers are well suited to develop lab-onchip devices [5,6].…”

Section: Introductionmentioning

confidence: 99%

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Conic optical fiber probe for generation and characterization of microbubbles in liquids

Muñoz-Pérez

Cruz

Andrés

et al. 2021

Sensors and Actuators A: Physical

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A novel optical fiber probe has been developed to provide mechanical stability to microbubbles generated in fluids, the tip of the fiber is etched with hydrofluoric acid to pierce a truncated horn that fastens the microbubbles to the fiber tip and prevents misalignment or detachment caused by convection currents, vibrations or shocks in the liquid. Microbubbles are photothermally generated on the etched fiber and used as Fabry-Perot cavity sensor. Two methods were used to interrogate the probe: the first one, in the wavelength domain, is suitable for calibration in static or quasi static situations; the second one, in the time domain, can be used in dynamic environments. Experimental results in the wavelength domain show that the microbubble size rises linearly with temperature and decreases with the inverse of pressure; the average slopes are 27.1 m/ 0 C and 88.3m/bar respectively. Dynamic variations of temperature have been measured in the time domain, temperature changes down to 0.007 0 C have been detected at a readout rate of 10 s -1 . Bubbles have been subjected to pressure shocks of 2.4 bar at a speed of 25 bar/s, pressure changes of 3.4 mbar have been resolved in the time domain at a readout rate of 20000 s -1 .

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Section: Resultsmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

Conic optical fiber probe for generation and characterization of microbubbles in liquids

Muñoz-Pérez

Cruz

Andrés

et al. 2021

Sensors and Actuators A: Physical

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“…3 Within the last few years much effort has been devoted to increasing the degree of integration at reasonable cost and therefore the number and complexity of possible application cases via integrating multifunctionalities and bio-sensors onto microuidic chips. [4][5][6] Some examples are: on-chip integrated micro-pumps were integrated by fully inkjet-printed piezoelectric membrane pumps 7,8 to drive the uid with analytes through microchannels; inkjet printed micro-heaters [9][10][11] were integrated to realize the thermal control for analysis; inkjet printed SERS pads were integrated to increase Raman signals; 12 the analyte mixing and separating can be digitally controlled by inkjetprinted digital microuidics; 13,14 even micro-channels can be directly printed on paper. 15,16 Fluorescent sensing is the most common analytical and diagnostic method in biological and medical applications because of high sensitivity and selectivity.…”

Section: Introductionmentioning

confidence: 99%

Highly sensitive on-chip fluorescence sensor with integrated fully solution processed organic light sources and detectors

et al. 2017

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We report the first fluorescence light detector combining a fully solution processed organic electrochemical cell (OLEC) and a fully solution processed organic photodiode (OPD) within one microfluidic chip. The blue OLEC was used as the excitation source, whereas the OPD was used for detection of the emitted fluorescent light. Two orthogonally oriented linear polarizers were used as excitation and emission filters, enabling the use of fluorescent dyes with emission and absorption peaks very close to each other. In addition the system is compatible with many different fluorescent dyes. The filters and organic devices were mounted onto a microfluidic glass chip. Fluorescein amidite (FAM) was used as a model dye to characterize and demonstrate the concept of the system. Despite a very close excitation peak (492 nm) and emission peak (518 nm) of FAM, we were able to detect FAM concentrations as low as 1 μM even for a brightness value of the OLEC as low as 500 cd m -2. This opens the possibility of producing low cost, portable and disposable fluorescence sensors with a high sensitivity

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“…The introduction of an array of thermistors facilitated a large expansion of the dynamic range. With the use of fluorescent dyes, Hoera et al [ 19 ] developed a flow sensor based on temperature distribution imaging, that had a wide dynamic range of 10 nL/min to 100 μL/min. Unfortunately, the use of fluorescent dyes impose restrictions on the flow rate sensor in non-labeled detection fields.…”

Section: Introductionmentioning

confidence: 99%

A Novel Microfluidic Flow Rate Detection Method Based on Surface Plasmon Resonance Temperature Imaging

Deng

Wang

Liu

et al. 2016

Sensors

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A novel microfluidic flow rate detection method based on surface plasmon resonance (SPR) temperature imaging is proposed. The measurement is performed by space-resolved SPR imaging of the flow induced temperature variations. Theoretical simulations and analysis were performed to demonstrate a proof of concept using this approach. Experiments were implemented and results showed that water flow rates within a wide range of tens to hundreds of μL/min could be detected. The flow rate sensor is resistant to disturbances and can be easily integrated into microfluidic lab-on-chip systems.

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A chip-integrated highly variable thermal flow rate sensor

Cited by 22 publications

References 60 publications

Conic optical fiber probe for generation and characterization of microbubbles in liquids

Conic optical fiber probe for generation and characterization of microbubbles in liquids

Highly sensitive on-chip fluorescence sensor with integrated fully solution processed organic light sources and detectors

A Novel Microfluidic Flow Rate Detection Method Based on Surface Plasmon Resonance Temperature Imaging

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