“…3 Nowadays, DBT is used not only as an efficacious medicine, but also as a common food supplement. Previous studies have demonstrated that DBT has attractive pharmacological activities, including immunoregulation, 4 estrogenic properties, 5 anti-inflammation, 6 stimulation of the T-lymphocytes proliferation, 7 regulating blood lipid and foam cell formation, 8 as well as retarding the progress of diabetic nephropathy. 9 In recent years, metabolism studies of CHMs have attracted significant attention, as they shed additional light on drug efficacy, 10 and enable the screening of bioactive components, 11 the detection of potentially toxic metabolites, 12 the elucidation of herb-drug interactions, 13 and the identification of drug degradation pathways.…”