volume 66, issue 9, P5509-5515 1992
DOI: 10.1128/jvi.66.9.5509-5515.1992
View full text
|
Sign up to set email alerts
|
Share

Abstract: This report describes a novel method for complementation studies of defective herpes simplex virus (HSV) genes. Viral test gene and nonviral reporter gene cassettes were rapidly integrated into the HSV genome in a site-specific and reversible manner by using the P1 phage-based Cre-ox recombination system. Shuttle plasmids contained a functional loxP recombination site, an expressible form of the bacterial lacZ gene, and a copy of the wild-type glycoprotein B (gB) gene or double mutant gB allele containing both…

Expand abstract

Search citation statements

Order By: Relevance

Citation Types

1
10
0

Paper Sections

0
0
0
0
0

Publication Types

0
0
0
0

Relationship

0
0

Authors

Journals