A Case of Seborrhoeic Blepharitis.

Ninomiya, Junya; Takahashi, Chisako; Nakabayasi, Atsuhiro; Teramoto, Teruyo; Takiuchi, Iwao; Tahara, Kazumi

doi:10.3314/jjmm.41.121

Cited by 3 publications

(3 citation statements)

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“…Of the 21 publications identified, nine were for itraconazole, three for terbinafine, three for fluconazole, two for ketoconazole, and one for each of pramiconazole, predinisone, isotretinoin and homeopathic mineral therapy . Case reports and studies without the full text availability were not evaluated for quality.…”

Section: Resultsmentioning

confidence: 99%

“…Five studies were RCTs with a MQS varying between 13.5 and 22.0 on a possible 28 point scale. Ten were open studies with a MQS varying between 8.5 and 13.5 and six were case reports …”

Section: Resultsmentioning

confidence: 99%

“…Six open non‐comparative trials and three case studies were identified for itraconazole (Table ). The MQS for the open non‐comparative studies ranged from 10.5 to 13.5 on a possible 28 point scale.…”

Section: Resultsmentioning

confidence: 99%

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Systematic Review of Oral Treatments for Seborrheic Dermatitis

Gupta

Richardson

Paquet

2013

Acad Dermatol Venereol

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Seborrheic dermatitis (SD) is normally treated with topical corticosteroids and antifungals. Oral therapies can be prescribed in severe or unresponsive cases. This review aims to assess the quantity and quality of published reports on oral therapies for SD. MEDLINE and Embase databases and the reference listings of publications were searched for any publication using oral treatment for SD. The quality of the included publications was assessed using a modified 27 item checklist by Downs and Black. Twenty-one publications (randomized controlled trials, open trials and case reports) covering eight oral therapies (itraconazole, terbinafine, fluconazole, ketoconazole, pramiconazole, prednisone, isotretinoin and homeopathic mineral therapy) were identified. Most of the publications investigated oral antifungals and the quality of the evidence was generally low. The clinical efficacy outcome reported varied considerably between the studies, preventing statistical analysis and direct comparison between treatments. However, ketoconazole therapy was associated with more relapses compared with other treatments. Itraconazole dosing regimen for SD was generally 200 mg/day for the first week of the month followed by 200 mg/day for the first 2 days for 2-11 months. Terbinafine was prescribed at 250 mg/day either as a continuous (4-6 weeks) or as an intermittent regimen (12 days per month) for 3 months. Fluconazole has administered daily (50 mg/day for 2 weeks) or weekly (200-300 mg) for 2-4 weeks. Ketoconazole dosing regimen was 200 mg daily for 4 weeks. Finally, a single 200 mg dose of pramiconazole was administered to patients. This review also highlights key areas for consideration when designing future studies.

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Section: Resultsmentioning

confidence: 99%

“…Five studies were RCTs with a MQS varying between 13.5 and 22.0 on a possible 28 point scale. Ten were open studies with a MQS varying between 8.5 and 13.5 and six were case reports …”

Section: Resultsmentioning

confidence: 99%