A Case of Retinal Hemorrhage Following a Dexamethasone Intravitreal Implant

Abstract

Purpose:To report a case of retinal hemorrhage after a dexamethasone (Ozurdex ® , Allergan, Irvine, CA, USA) intravitreal implant injection in macular edema (ME) secondary to central retinal vein occlusion (CRVO). Case summary: A 60-year-old woman visited our hospital for ME secondary to CRVO in the right eye. Intravitreal bevacizumab injection and vitrectomy was conducted three times, but ME did not improve. Then, dexamethasone intravitreal implant was injected without any problems. Right after the dexamethasone intravitreal implant injection, retinal hemorrhage (2 disc diopter size) was observed in the infero-temporal area on fundus examination. Retinal hemorrhage completely disappeared 1 month after injection without other treatment.

Retina Injury After Dexamethasone Injection Into a Vitrectomized Eye

“…Additional cases have described this occurrence with complications during the injection procedure. [1][2][3] Two cases of vitrectomized eyes without complications in the injection procedure are summarized as follows: in a case from Italy, a dexamethasone implant struck the inferior temporal arcade, prophylactic laser demarcation was performed, and by 3-month follow-up the vision returned to baseline 1 ; and in a case from Korea, a dexamethasone implant lodged in the retina after injection and was followed by prophylactic laser demarcation, and there were no complications at 1-month follow-up. 2 Our case represents the first reported instance in which retinal impact by On review of this case, there appear to be 2 leading possibilities as to how this complication may have occurred.…”