A Case of Postural Orthostatic Tachycardia Syndrome Associated with Migraine and Fibromyalgia

Yun, Dong Hwan; Choi, Han Gon; Oh, Gun Sei

doi:10.3344/kjp.2013.26.3.303

Cited by 2 publications

(1 citation statement)

References 10 publications

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“…Moreover, dysautonomia has been considered to fall into the above mentioned “central sensitivity syndromes” [ 8 ]. Hence, FM could be associated with specific types of dizziness occurring in dysautonomic conditions, like for example the one experienced by patients suffering from Postural Orthostatic Tachycardia Syndrome (POTS) [ 44 ].…”

Section: Discussionmentioning

confidence: 99%

Vestibular Disability/Handicap in Fibromyalgia: A Questionnaire Study

Mucci

Demori

Rapallo

et al. 2022

JCM

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Fibromyalgia (FM) is a poorly understood, central pain processing disorder characterized by a broad range of symptoms, such as chronic pain, sleep disruption, chronic fatigue, and psychosomatic symptoms. In addition, recent studies have shown that FM patients also experience dizziness. We aimed to establish a prevalence rate of vestibular symptoms in a population of FM patients through a battery of questionnaires investigating socio-demographic, clinical and psychological characteristics, combined with the Dizziness Handicap Inventory (DHI) and the Situational Vertigo Questionnaire (SVQ). A total of 277 respondents, officially diagnosed with FM, completed the full study, while 80 controls were also included for DHI and SVQ questionnaires. We found that FM participants were significantly affected by vestibular symptoms, which correlated with FM-associated pain and non-pain symptoms. The dizziness reported by FM participants showed peculiar features suggesting an FM-intrinsic mechanism of vestibular dysfunction, possibly linked to migraine and dysautonomia conditions. Correlations between dizziness and depressive mood (or neuroticism), revealed an impact of dizziness on psychological status, leading to depressive reactions and interpersonal difficulties, and possibly involving a noxious, self-sustained stress condition. In conclusion, data showed a manifesting dizziness condition in FM patients that warrants careful clinical attention due to its possible inherent role in the syndrome.

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Section: Discussionmentioning

confidence: 99%

Vestibular Disability/Handicap in Fibromyalgia: A Questionnaire Study

Mucci

Demori

Rapallo

et al. 2022

JCM

View full text Add to dashboard Cite

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Impact of Comorbidities on the Prognosis of Pediatric Postural Tachycardia Syndrome

Wang¹,

Du²,

Li³

et al. 2021

IJGM

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Objective To investigate the influence of comorbidities on the prognosis of pediatric postural tachycardia syndrome (POTS). Methods In this retrospective cohort study, 275 children with POTS admitted to the Department of Pediatrics at Peking University First Hospital were recruited from 2016 to 2019 and followed up. The participants were divided into simple POTS (S-POTS, n=156 cases) and POTS with comorbidities (Co-POTS, n=119 cases) groups according to whether they were complicated with comorbidities. A Cox regression analysis was used to identify the prognostic risk factors for children with POTS, while Kaplan–Meier curves were applied to compare the cumulative symptom remission rate (CSRR) between the two groups. The rehospitalization of the children between the two groups was also compared to explore the influence of comorbidities. Results Twenty-one participants (7.6%) were lost during a median follow-up of 24 months. The Cox regression model showed that comorbidities and body mass index (BMI) were associated with the CSRR of the children with POTS. The CSRR of pediatric POTS alone was 1.748 times higher than that of patients with comorbidities, and the CSRR was decreased by 5.1% for each 1 kg/m 2 increase in BMI. The most common comorbidity in children with POTS in this study was allergic disorders, followed by the psychological diseases. The patients in the Co-POTS group had a lower CSRR than those in the S-POTS group (log rank P=0.0001). In addition, compared with those of the S-POTS group, the total number of rehospitalizations was high (P=0.001), and the total hospital stays were long in the Co-POTS group (P<0.001). Conclusion Complicating with comorbidities, pediatric patients with POTS had lower CSRR and more rehospitalizations than those without comorbidities. More attention should be given to comorbidities when managing pediatric POTS.

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A Case of Postural Orthostatic Tachycardia Syndrome Associated with Migraine and Fibromyalgia

Cited by 2 publications

References 10 publications

Vestibular Disability/Handicap in Fibromyalgia: A Questionnaire Study

Vestibular Disability/Handicap in Fibromyalgia: A Questionnaire Study

Impact of Comorbidities on the Prognosis of Pediatric Postural Tachycardia Syndrome

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