A Case of "Hot Tub Lung" Due to Mycobacterium avium Complex in an Immunocompetent Host

Cappelluti, Erika; Fraire, Armando E.; Schaefer, Oren P.

doi:10.1001/archinte.163.7.845

Cited by 47 publications

(26 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There is a continuing debate on optimal management of these patients [71]. The fact that a high rate of patients have been reported to be cured by avoidance of the antigen and/or corticosteroid therapy without antimycobacterial therapy suggests that hot tub lung is more likely a form of hypersensitivity pneumonitis than an infectious disease [72,73,74]. …”

Section: Clinical Presentationmentioning

confidence: 99%

Pulmonary Disease Caused by Non-Tuberculous Mycobacteria

Wassilew¹,

Hoffmann²,

Andréjak³

et al. 2016

Respiration

125

View full text Add to dashboard Cite

Non-tuberculous mycobacteria (NTM) include more than 160 ubiquitous, environmental, acid-fast-staining bacterial species, some of which may cause disease in humans. Chronic pulmonary infection is the most common clinical manifestation. Although patients suffering from chronic lung diseases are particularly susceptible to NTM pulmonary disease, many affected patients have no apparent risk factors. Host and pathogen factors leading to NTM pulmonary disease are not well understood and preventive therapies are lacking. NTM isolation and pulmonary disease are reported to rise in frequency in Europe as well as in other parts of the world. Differentiation between contamination, infection, and disease remains challenging. Treatment of NTM pulmonary disease is arduous, lengthy, and costly. Correlations between results of in vitro antibiotic susceptibility testing and clinical treatment outcomes are only evident for the Mycobacterium avium complex, M. kansasii, and some rapidly growing mycobacteria. We describe the epidemiology of NTM pulmonary disease as well as emerging NTM pathogens and their geographical distribution in non-cystic fibrosis patients in Europe. We also review recent innovations for the diagnosis of NTM pulmonary disease, summarize treatment recommendations, and identify future research priorities to improve the management of patients affected by NTM pulmonary disease.

show abstract

Section: Clinical Presentationmentioning

confidence: 99%

Pulmonary Disease Caused by Non-Tuberculous Mycobacteria

Wassilew¹,

Hoffmann²,

Andréjak³

et al. 2016

Respiration

125

View full text Add to dashboard Cite

show abstract

“…In Japan, among 273 newly diagnosed MAC-PD cases between 1996 and 2002, 70.3% were female with a mean age of 63.2 years (Okumura et al, 2008). The HRCT findings of MAC-PD also exhibit all three forms of lung disease, as described for NTM-PD, namely cavitary disease, fibronodular bronchiectasis, and HP (Cappelluti et al, 2003;Embil et al, 1997;Glassroth, 2008;Kahana et al, 1997). Fibronoduar bronchiectasis caused by MAC is most frequently observed in women >60 years old, and compared to patients with other types of NTM infection, the lingual and right middle lobe tend to be more severely and progressively involved (Hollings et al, 2002;Kim et al, 2005;Kubo et al, 1998;Obayashi et al, 1999;Prince et al, 1989;Tanaka et al, 2001).…”

Section: Mycobacterium Avium Complexmentioning

confidence: 92%

Nontuberculous Mycobacterium Infections in Rheumatoid Arthritis Patients

Watanabe¹,

Banno²

2012

Rheumatoid Arthritis - Etiology, Consequences and Co-Morbidities

View full text Add to dashboard Cite

“…The results of NTM PCR, however, were all negative. Some NTM infections associated with bathing water have been reported (9,10). Two of the patients had visited differ- ent public bathhouses after operation.…”

mentioning

confidence: 99%

Three Cases of Postoperative Septic Arthritis Caused by Mycobacterium conceptionense in the Shoulder Joints of Immunocompetent Patients

et al. 2014

View full text Add to dashboard Cite

e Mycobacterium conceptionense is a species member of Mycobacterium fortuitum complex, a potential pathogen of increasing clinical importance among opportunistic infections. This species causes a wide spectrum of cutaneous and extracutaneous diseases. In this report, we describe three patients who underwent shoulder surgery with postoperative joint infection by M. conceptionense. CASE REPORTSC ase 1 was a 72-year-old man admitted due to painful swelling of his right shoulder of 5 days' duration. One month prior to this admission, he had undergone arthroscopic rotator cuff repair for a rotator cuff tear in the right shoulder. He had tested seronegative for human immunodeficiency virus (HIV) before operation. A magnetic resonance image (MRI) of the right shoulder indicated fluid accumulation around a thickened synovium with prominent contrast enhancement. Incision and debridement of this infectious lesion were performed, which yielded turbid exudative fluid. He was started on cefazolin. On the 5th day of admission, Gram-positive rods and acidfast bacilli (AFB) were identified from the intraoperative culture samples. At that time, arthroscopic debridement was carried out because the wound on the right shoulder worsened despite the initial drainage and treatment with intravenous antibiotics. The intraoperative sample from arthroscopic debridement returned positive for AFB staining and nontuberculous mycobacteria (NTM) on PCR.On the 7th day after the second operation, the mycobacterial culture of discharge and tissue yielded

show abstract

A Case of "Hot Tub Lung" Due to Mycobacterium avium Complex in an Immunocompetent Host

Cited by 47 publications

References 21 publications

Pulmonary Disease Caused by Non-Tuberculous Mycobacteria

Pulmonary Disease Caused by Non-Tuberculous Mycobacteria

Nontuberculous Mycobacterium Infections in Rheumatoid Arthritis Patients

Three Cases of Postoperative Septic Arthritis Caused by Mycobacterium conceptionense in the Shoulder Joints of Immunocompetent Patients

Contact Info

Product

Resources

About