A case of bullous pemphigoid clinically mimicking subcorneal pustular dermatosis

Abstract

has been missed by this screen. However, a more likely explanation is that there are other genes involved in DC, particularly in the autosomal-recessive form of the disease, the identities of which remain unknown. A recent study showed that two thirds of the families included such as our patient did not have mutations in DKC1 and TERC genes. 4 Cutaneous findings are the most consistent feature of DC. The degree of pigmentation increases with age and can involve the entire skin surface. Dermal pigmentation was reported in the cases with DC in the literature. 5 We demonstrated hyperkeratinization in the dermis and basal pigmentation in the epidermis, but there was no dermal pigmentation in our case. Lack of dermal pigmentation is not inconsistent with DC, since the physical appearance can be highly variable.Our patient had unilateral renal agenesis. A patient with DC and horseshoe kidney was previously reported. 6 Renal agenesis occurs in 1 of 1000 births; thus, it may be a coincidental finding.In this report, we present an atypical case with DC and unilateral renal agenesis from Turkey. Reporting cases with DC will highlight the mechanisms underlying a broad range of biological processes like ageing and many forms of cancer.

Dapsone-responsive inflammatory dermatitis with features of subcorneal pustular dermatosis and bullous pemphigoid

“…9 Interestingly, a case of BP mimicking SPD has been reported. 10 BP may have a propensity to develop in patients with SPD, as for instance in patients with psoriasis. Alternatively, this patient's immunopathology findings may have developed secondary to his chronic, treatment-resistant skin disease, representing an atypical response to prior therapies, or signifying subclinical BP.…”