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Cited by 266 publications
(193 citation statements)
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“…These contributions include those of Weinbaum et al (1994), Cowin et al (1995), Swan et al (2003), Rémond & Naili (2005) and Rémond et al (2008). Two recent papers have computationally addressed the question of the two interacting porosities.…”
Section: Discussionmentioning
confidence: 99%
“…These contributions include those of Weinbaum et al (1994), Cowin et al (1995), Swan et al (2003), Rémond & Naili (2005) and Rémond et al (2008). Two recent papers have computationally addressed the question of the two interacting porosities.…”
Section: Discussionmentioning
confidence: 99%
“…This results in bone cells being exposed to an oscillating fluid flow. Theoretical models have been advanced suggesting that information regarding mechanical loading is perceived by bone cells through loading-induced oscillatory fluid flow (Kufahl and Saha, 1990;Weinbaum et al, 1994;Cowin et al, 1995), including the wall shear stress in the marrow compartment (Swan et al, 2003). These theoretical models also predict that bone cells are exposed to fluid induced shear stress that is on the order of 0.8 to 3 Pa in vivo (Weinbaum et al, 1994) (a paschal is force per area, where 1 Pa = N/m 2 ).…”
Section: What Mechanical Factors Are Generated By Loading?mentioning
confidence: 99%
“…It has been hypothesized that bone remodeling is controlled at the cellular level through signals mediated by osteocytes [25]. This hypothesis has been supported by results from in vitro experiments by You et al [26,27] in which bone cells were subjected to a fluid flow generated by shear stresses. The results of an in vivo experimental study by Vashishth et al [28] support the sensory role of osteocytes in human cortical bone and the decline of the osteocyte lacunar density caused by an accumulation of microcracks.…”
Section: Model Based On Ruptured Osteocyte Processes (Roc)mentioning
confidence: 95%