A Case‐control Study of Smoking and Alzheimer's Disease

Abstract

The study supports previous findings of an inverse relationship between smoking and Alzheimer's disease. This, however, does not suggest that smoking is used as a preventive measure for Alzheimer's disease.

Cognitive impairment and risk factor prevalence in a population over 60 in Argentina

“… 41 The meta-analysis performed by Mortimer 42 with data from seven case-control studies, indicated that a tobacco-AD association was improbable. Other case-control and longitudinal studies 43 , 44 as well as reviews 45 , 46 suggest a possible protective effect of cigarettes for AD. The Rotterdam 40 study found that smoking doubles the risk for dementia and AD.…”

Smoking as a risk factor for Alzheimer’s disease: contrasting evidence from a systematic review of case–control and cohort studies

“…Bias may also be introduced in case–control studies that select controls from clinical samples (Chandra et al 1987; Salib & Hillier 1997). Subjects in contact with medical services are more likely to display smoking health‐related problems (e.g.…”

Simultaneous Inference in General Parametric Models

“…0.1 ' ' 1 (Adjusted p values reported --single-step method) and the result reported above holds under very mild model assumptions. Salib and Hillier (1997) report results of a case-control study on Alzheimer's disease and smoking behavior of 198 female and male Alzheimer patients and 164 controls. The alzheimer data have been re-constructed from Table˜4 in Salib and Hillier (1997).…”

“…Salib and Hillier (1997) report results of a case-control study on Alzheimer's disease and smoking behavior of 198 female and male Alzheimer patients and 164 controls. The alzheimer data have been re-constructed from Table˜4 in Salib and Hillier (1997). The authors conclude that 'cigarette smoking is less frequent in men with Alzheimer's disease.'…”