Abstract:Galactosylceramide (GalCer) and cerebroside sulfate (CBS) are the major glycolipids found in myelin. They occur in greater concentrations in this membrane than any other. Recently, it was reported that these two glycolipids can participate in a heterotypic carbohydrate-carbohydrate interaction [Hakomori et al. (1991) Glycoconjugate J. 8, 178]. In the present study, the effect of changes in the ceramide composition of both GalCer and CBS on this interaction has been examined. The interaction was monitored by me… Show more
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