A Camel Milk Whey Protein Rich in Half‐cystine

Beg, Obaid Ullah; Bahr‐Lindström, Hedvig von; Zaidi, Zafar H.; Jörnvall, Hans

doi:10.1111/j.1432-1033.1986.tb09853.x

Cited by 27 publications

(32 citation statements)

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“…The lack of coagulum formation of camel milk may also be helpful in taking the insulin present in it unchanged to intestine where it can be absorbed even if some amount is destroyed in the passage. Beg et al (1986) have found that amino-acid sequence of some of the camel milk protein is rich in half-cystine, which has superficial similarity with insulin family of peptides.…”

Section: Resultsmentioning

confidence: 99%

Effect of camel milk on glycemic control and insulin requirement in patients with type 1 diabetes: 2-years randomized controlled trial

et al. 2011

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Background/Objectives: Hypoglycemic effect of camel milk supplementation in experimental rat model and significant reduction in doses of insulin in type 1 diabetic patients have been observed in our previous studies. This long-term study was undertaken to assess the efficacy, safety and acceptability of camel milk as an adjunct to insulin therapy in type 1 diabetics. Subjects/Methods: In this 2-year randomized clinical, parallel design study, 24 type 1 diabetics were enrolled and divided into two groups. Group I (n ¼ 12) received usual care, that is, diet, exercise and insulin and Group II (n ¼ 12) received 500 ml camel milk in addition to the usual care. Insulin requirement was titrated weekly by blood glucose estimation. Results were analyzed by using the regression technique. Results: In camel milk group, there was decrease in mean blood glucose (118.58 ± 19-93.16 ± 17.06 mg/dl), hemoglobin A1c levels (7.81 ± 1.39-5.44 ± 0.81%) and insulin doses (32.50 ± 9.99-17.50 ± 12.09 U/day, Po0.05). Out of 12 subjects receiving camel milk, insulin requirement in 3 subjects reduced to zero. There was nonsignificant change in plasma insulin and anti-insulin antibodies in both the groups. Conclusion: It may be stated that camel milk is safe and efficacious in improving long-term glycemic control, with a significant reduction in the doses of insulin in type 1 diabetic patients.

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Section: Resultsmentioning

confidence: 99%

Effect of camel milk on glycemic control and insulin requirement in patients with type 1 diabetes: 2-years randomized controlled trial

et al. 2011

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“…The presence of high concentration of insulin/insulin-like substances in camel milk such as half-cystine [15], the effect of small-sized immunoglobulins of camel milk on bcell [7] and the lack of coagulation of camel milk in the human stomach contribute to the hypoglycemic effect in type 1 diabetes in human [6], rats [99] as well as in alloxaninduced diabetic dogs [102].…”

Section: Camel Milk Adjuvant For Management Of Diabetesmentioning

confidence: 99%

Camel Milk: An Important Natural Adjuvant

et al. 2017

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One humped camel (Camelus dromedarius) breeds, indigenous to India, have been shown to have good genetic potential to produce milk. Camel milk not only is cost-effective in terms of feed conversion but also has additional advantage of longer lactation period and unique adaptation mechanisms for warm arid and semiarid regions. The key features of camel milk in comparison with other milk are low fat with high content of unsaturated and long-chain fatty acid. The proteins are rich in lactoferrin and lysozymes, but deficient in b-lactoglobulin. It has higher percentage of total salts, free calcium, protective proteins and vitamin C, and some of the microminerals, viz iron, copper and zinc. Physicochemical properties of camel milk are also unique and useful for food processing. The shelf life of raw camel milk is 8-9 h, which can be extended up to 18-20 h through activation of camel lactoperoxidase system. Heat stability of camel milk is shown to be highest at pH 6.8, and it ferments relatively slowly compared to the cattle milk. The camel milk is successfully processed for producing a variety of products, such as fermented milk ('lassi'), soft cheese, flavored milk and 'kulfee' (a kind of ice cream). Camel milk has been traditionally used in different regions of the world as natural adjuvant for managing a variety of human diseases.

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“…Not only can camels survive under conditions of severe water and heat stress, but they also provide an important source of nutrients in desert communities, especially important during periods of prolonged drought (Farah, 1993). Available information concerning dromedary milk (Farah and FarahRiesen, 1985;Beg et al, 1984Beg et al, , 1986aBeg et al, , b, 1987Mehaia, 1987;Mohammed andLarssonRaznikiewicz, 1989, 1991;Farah, 1993;Alim et al, 2005;Zhang et al, 2005;Konuspayeva et al, 2009;Al-Haj et al, 2010;Ereifej et al, 2011) is related mainly to the Arabian dromedary Camelus dromedaries species. The present work has been carried out in order to present a more description of the major milk proteins from Algerain dromedary's milk.…”

Section: Introductionmentioning

confidence: 99%

Separation and characterization of major milk proteins from Algerian<br>Dromedary (Camelus dromedarius)

Saliha

Dalila

Chahra

et al. 2013

Emir. J. Food Agric

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To characterize major protein fraction in Algerian dromedary's milk, two samples from Sahraoui population collected from two different regions were analyzed using electrophoretic and chromatographic techniques. Casein components and whey proteins were separated by DEAE-cellulose ion exchange chromatography and Sephacryl S200 permeation gel chromatography respectively, and then identified by polyacrylamide gel electrophoresis which looked different from the corresponding patterns of the caseins and whey proteins from cow milk. Differences in casein composition between camel and bovine milk may influence their digestibility, hydrolysis of camel milk caseins using four different proteases (trypsin, chymotrypsin, pepsin and papain) was studied. Caseins were more rapidly hydrolyzed by pepsin because of the greater number of potential pepsin cleavage sites present in the primary structures of camel caseins.

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A Camel Milk Whey Protein Rich in Half‐cystine

Cited by 27 publications

References 0 publications

Effect of camel milk on glycemic control and insulin requirement in patients with type 1 diabetes: 2-years randomized controlled trial

Effect of camel milk on glycemic control and insulin requirement in patients with type 1 diabetes: 2-years randomized controlled trial

Camel Milk: An Important Natural Adjuvant

Separation and characterization of major milk proteins from Algerian<br>Dromedary (Camelus dromedarius)

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