A bubble-assisted electroosmotic micropump for a delivery of a droplet in a microfluidic channel combined with a light-addressable potentiometric sensor

Li, Xueliang; Liu, Shibin; Fan, Pingping; Werner, Carl Frederik; Miyamoto, Ko Ichiro; Yoshinobu, Tatsuo

doi:10.1016/j.snb.2017.02.165

Cited by 19 publications

(13 citation statements)

References 25 publications

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“…In order to improve the infusion efficiency of the electroosmotic micropump, Li Xueliang et al proposed a technology of a bubble-assisted electroosmotic micropump and used it to construct a microelectrochemical analysis system ( Li et al, 2017 ). As shown in Figure 10 , the microelectrochemical analysis system includes three sections—a bubble-assisted electro-osmotic micropump section, a microdroplet separation section, and a LAPS detection section.…”

Section: Research Progress Of the Laps In A Microelectrochemical Anal...mentioning

confidence: 99%

Light-Addressable Potentiometric Sensors in Microfluidics

Liu

Tan

et al. 2022

Front. Bioeng. Biotechnol.

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The light-addressable potentiometric sensor (LAPS) is an electrochemical sensor based on the field-effect principle of semiconductors. It is able to sense the change of Nernst potential on the sensor surface, and the measuring area can be controlled by the illumination of a movable light. Due to the unique light-addressable ability of the LAPS, the chemical imaging system constructed with the LAPS can realize the two-dimensional image distribution detection of chemical/biomass. In this review, the advantages of the LAPS as a sensing unit of the microelectrochemical analysis system are summarized. Then, the most recent advances in the development of the LAPS analysis system are explained and discussed. In particular, this review focused on the research of ion diffusion, enzymatic reaction, microbial metabolism, and droplet microfluidics using the LAPS analysis system. Finally, the development trends and prospects of the LAPS analysis system are illustrated.

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Section: Research Progress Of the Laps In A Microelectrochemical Anal...mentioning

confidence: 99%

Light-Addressable Potentiometric Sensors in Microfluidics

Liu

Tan

et al. 2022

Front. Bioeng. Biotechnol.

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“…Finally, when the micro-droplets reach the detection area of LAPS, the electroosmotic micropump is closed and the LAPS detection system is started to complete the micro-droplet detection. [36] In order to improve the infusion efficiency of electroosmotic micropump, Li Xueliang et al proposed a technology of bubble-assisted electroosmotic micropump, and used it to construct a microelectrochemical analysis system [37] . As shown in Figure 10, the microelectrochemical analysis system includes 3 sections-a bubble-assisted electroosmotic micropump section, a micro-droplet separation section, as well as a LAPS detection section.…”

Section: Digital Droplet Laps Microanalysis Systemmentioning

confidence: 99%

“…When the droplets are separated in the "bottleneck" area which is in the downstream of the microchannels, by bubble-assisted electroosmotic micropump, the microdroplets are pumped to the detection area of LAPS and contact with the reference electrode of LAPS to complete the droplets detection. [37] 3…”

Section: Digital Droplet Laps Microanalysis Systemmentioning

confidence: 99%

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Light-Addressable Potentiometric Sensors in Microfluidics

li¹,

liu²,

Tan³

et al. 2021

Preprint

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Light-addressable potentiometric sensor (LAPS) is an electrochemical sensor based on the field-effect principle of semiconductor. It is able to sense the change of Nernst potential on the sensor surface, and the measuring area can be controlled by the illumination. Due to the unique light-addressable ability of LAPS, the chemical imaging system constructed with LAPS can realize the two-dimensional image distribution detection of chemical/biomass. In this paper, the advantages of LAPS as sensing unit of microelectrochemical analysis system are summarized. Then, the greatest development of LAPS analysis system is explained and discussed. Especially, this paper focused on the research of ion diffusion, enzymatic reaction, microbial metabolism and droplet microfluidics by using LAPS analysis system. Finally, the development trends and prospects of LAPS analysis system are illustrated.

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“…25,26 In recent years, EO-pumps receive increasing attention in microfluidics since they have several unique features compared to other micropumps: they generate constant pulse-free flows, their flow magnitude and direction are convenient to control, they are readily integrated with lab-on-chip devices, and they have no moving parts. [27][28][29][30][31][32] In contrast to previous work that utilized EO-flow (EOF) to drive flow in already wet membranes, we here investigate the use of EO pumping for dynamic control of capillary flows during the filling process in paperbased devices. We present an analytical model for the distance penetrated by the liquid in porous media affected by the application of an integrated EO-pump and characterized the deviation from Lucas-Washburn flow.…”

Section: Introductionmentioning

confidence: 99%