volume 48, issue 10, P2754-2764 2015
DOI: 10.1021/acs.accounts.5b00273
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Abstract: CONSPECTUS A large class of heme and nonheme metalloenzymes utilize O2 or its derivatives (e.g. H2O2) to generate high-valent metal-oxo intermediates for performing challenging and selective oxidations. Due to their reactive nature, these intermediates are often short-lived and very difficult to characterize. Synthetic chemists have sought to prepare analogous metal-oxo complexes with ligands that impart enough stability to allow for their characterization and an examination of their inherent reactivity. The …

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