A 26-Year-Old Man With an Eczematous Lesion on the Nipple—Quiz Case

Clear Cell Acanthoma on the Areola

“…The preferred treatment options have been surgical resection and cryotherapy with no recurrences observed [2]. Additionally, four cases were successfully treated with topical corticosteroids, leading to complete resolution over the course of several weeks, further supporting an inflammatory etiology for this lesion [9,10]. If CCA were truly a neoplastic process, treatment with corticosteroids would not be expected to lead to a resolution.…”

Bilateral clear cell acanthoma of the areola and nipple: good response to topical corticosteroids

“…CCA in the nipple area is uncommon; only 8 cases have ever been described. 2 , 3 , 4 , 8 , 9 In all cases it affected young patients aged 14-25 years; only 1 patient was male. In the present study, patient was a 16 year-old girl.…”

Clear cell acanthoma of the nipple: another report from Italy

“…I reported, in 2012, a similar case in Archives of Dermatology 5 : a young man, suffering from atopic dermatitis since infancy, was treated with topical steroids for months with signs of concentration of this dermatitis in the nipple-area complex. The histology revealed a clear cell acanthoma: the first one described in Europe.…”