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Sallam, Hassan; Agameya, Abdel-Fattah; Rahman, Ashraf Farrag; Ezzeldin, F.; Sallam, A.N.

doi:10.1023/a:1022905618883

Cited by 46 publications

(3 citation statements)

References 28 publications

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“…In contrast, Sallam et al ( 18 ) evaluated 784 IVF cycles, including 655 IVF-ICSI treatments, and found that negotiation of the cervix, the use of a vulsellum, and the presence of blood on the catheter wall or cervix did not affect CPR. Neithard et al ( 11 ) reported that ET performed with afterloading external guidance increased pregnancy rates when compared with difficult ETs, but this increase did not reach a statistically significant level in their retrospective evaluation of 127 IVF-ICSI cycles.…”

Section: Discussionmentioning

confidence: 98%

The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study

İnal¹,

İnal²

2021

tjod

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Objective: To investigate whether embryo transfer affects pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection (IVF-ICSI) treatment. Materials and Methods: A total of 2,257 patients who underwent IVF-ICSI treatment between 2012 and 2017 were included in this study. Subjects were categorized according to the embryo transfer technique that was required: group 1 (n=1,657) underwent easy transfer with a soft catheter; group 2 (n=548) received external guidance transfers; and group 3 (n=52) experienced difficult transfers with a stylet. Basal parameters, clinical and laboratory IVF-ICSI outcomes, and clinical pregnancy rates (CPR) were compared between the groups. Results: There were no differences between the groups in terms of age, body mass index, smoking status, duration and etiology of infertility, baseline folliclestimulating hormone, luteinizing hormone, estradiol (E 2 ), thyroid-stimulating hormone, prolactin levels, antral follicle count, duration of stimulation, stimulation protocol, total gonadotropin dose required, peak E 2 levels, progesterone levels, and endometrial thickness on human chorionic gonadotropin administration and transfer days (p>0.05). The numbers of oocytes retrieved, MII and 2PN, fertilization rate, day of embryo transfer, and CPRs were also comparable between the groups (p>0.05). Conclusion: Our data suggest that embryo transfer has no impact on pregnancy rates in patients who undergo IVF-ICSI treatment. Further studies with more participants are required to elucidate this situation.

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Section: Discussionmentioning

confidence: 98%

The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study

İnal¹,

İnal²

2021

tjod

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“…This finding is similar to study by Sallam et al . [12] in which blood at catheter tip was associated with reduced pregnancy rates. However, no difference was seen when transfer was difficult or extra manipulation like use of volsellum or cervical dilation was required.…”

Section: Discussionmentioning

confidence: 99%

Correlation of technical difficulty during embryo transfer with rate of clinical pregnancy

Singh¹,

Gupta²,

Mittal³

et al. 2012

J Hum Reprod Sci

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AIM:To correlate the ease or difficulty of embryo transfer and blood at catheter tip with pregnancy rate when embryo transfer (ET) was performed by the same operator using soft catheter.MATERIALS AND METHODS:A retrospective analysis of 342 patients who underwent in vitro fertilization or ICSI cycle from January 2008 to December 2010 in a single centre was done. The type of transfer was divided into two groups: ‘easy’ or ‘difficult’. Transfer was considered difficult when additional instrumentation was required or firmer catheter was used or required changing of catheter. Patients undergoing cryo-preserved ET were excluded from the study.RESULTS:On the day of transfer in 284 (83%) patients, ET was easy and difficulty was encountered in 58 (17%) patients. Blood at catheter was seen in 101 (29.53%) patients. In the group of 58 difficult transfers, 10 pregnancies resulted with a clinical pregnancy rate of 17.2%, while 67 pregnancies resulted in 284 cycles of easy transfer with clinical pregnancy rate of 23.6% (P value = 0.045). While no significant difference was seen in pregnancies with blood on outer catheter and blood less transfer, there was significant reduction in pregnancy rate when blood was present on catheter tip compared to bloodless transfer (13.3% v/s 24.1; P value = 0.032).CONCLUSION:Reduction in clinical pregnancy rate is seen with difficult ETs, more when blood is present at the catheter tip.

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“…As such, ICSI-AOA is an important approach in terms of offering the potential for a biological child, not least for patients whose religious beliefs do not permit sperm donation. 59 In these circumstances, AOA with calcium ionophore treatment after ICSI results in a statistically significant improvement in fertilization (105 cycles; 65.2–68.8% fertilization following ionophore AOA; p = 0.008), as well as clinical pregnancy (23.5–25.0%) and live birth rates (LBRs). 53 Nonetheless, patient selection is key, and is probably the biggest challenge to application of AOA as a treatment add-on, particularly given the absence of clinically validated and accessible diagnostic assays for PLCζ.…”

Section: Calcium Ionophorementioning

confidence: 99%

Artificial Egg Activation Using Calcium Ionophore

2021

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Artificial oocyte activation, most commonly using calcium ionophore, is a treatment add-on utilized to avoid recurrence of abnormally low or total failed fertilization following in vitro fertilization/intracytoplasmic sperm injection. It aims to modify defective physiological processes, specifically calcium-mediated cell signaling that are critical to events required for fertilization. Routine application of artificial oocyte activation is neither required nor recommended; however, it represents an invaluable intervention for a subgroup of patients affected by sperm-related oocyte activation deficiency.

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Abstract: Negotiation of the cervix, the use of a volsellum, and the presence of blood on the catheter wall or on the cervix do not affect the results. Changing the catheter and blood on the catheter tip significantly diminish the pregnancy and implantation rates. Soft catheters perform better.

Cited by 46 publications

References 28 publications

The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study

The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study

Correlation of technical difficulty during embryo transfer with rate of clinical pregnancy

Artificial Egg Activation Using Calcium Ionophore

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