Фототермическое действие инфракрасного (808 nm) лазерного излучения и наночастиц золота в различных модификациях на S. aureus

Abstract

The effect of infrared laser radiation (808 nm) of different fluence rates on the bacteria Staphylococcus aureus 209 P, incubated in solutions of gold nanocubes, nanorods and on glass substrates with fixed nanodiscs, was studied. Radiation with a power density of 60 mW/cm2 in combination with nanocubes caused the death of 50% of the bacterial population after 30 min of exposure, in combination with nanostructures - 56%. An increase in the temperature of suspended matter after irradiation was found of no more than 5-6 °C. Radiation with a power density of 400 mW/cm2 caused a pronounced inhibition of the viability of bacterial cells – by 81% after 30 min. Incubation of microorganism suspensions on the surface of glass substrate containing gold nanodiscs during irradiation (808 nm, 400 mW/cm2) resulted in 99% of bacterial cell death.