691 Clinico-Epidemiological Characteristics of Pediatric Esophagitis in Southern Iran: A Single Center Experience

Abstract

Material and methodology Authors have studied the seasonal distribution of the gastroenteritis caused by rotavirus. The study was prospective and was conducted at the Department of Pediatric Gastroenterology of the University Clinical Center of Kosova, during one year. Testing of the stool was performed using agglutination test with the sensitivity and specify of around 96%. Results Of 1011 children aged 0-5 years, hospitalized at the Department of Pediatric Gastroenterology due to gastroenteritis, 116 had rotavirus infection. At the admission all children were with diarrhea, 97.41% had vomiting and 43.96% had fewer. 70.7% of patients had moderate dehydration and 29.3% severe dehydration All patients in the study were intravenously rehydrated. All patients healed with no sequels. The seasonality of the disease was distinctive and had two peaks -first in late winter/early spring (January-16, February-9, March-9 and second in late summer/early autumn) August-11, September-20 and October-14. Conclusion Two peaks seasonality late winter/early spring and late summer/early autumn of the rotavirus infection reflects the difference in the wealth of the population in Kosova, with first peak in winter, similar to the one in the developed countries and the second peak in summer, similar to the one in non-developed countries. CLINICO-EPIDEMIOLOGICAL CHARACTERISTICS OF PEDIATRIC ESOPHAGITIS IN SOUTHERN IRAN: A SINGLE CENTER EXPERIENCEdoi:10.1136/archdischild-2012-302724.0691 M Zahmatkeshan, K Najib, B Geramizadeh, E Fallahzadeh, M Haghighat, MH Imanieh. Shiraz University of Medical Sciences, Shiraz, IranObjectives To determine the clinico-epidemiological characteristics of pediatric esophagitis in southern Iran. Methods A cross-sectional study was conducted during a 4-year period from 2005 to 2009 in Nemazee hospital, a tertiary healthcare center in Shiraz, southern Iran. We consecutively included all the pediatric patients (< 18 years) who underwent endoscopy in our center and had pathology-confirmed diagnosis of esophagitis. Data regarding the patients' demographic characteristics, comorbidities, and clinical findings were recorded using a questionnaire. All the patients underwent upper GI endoscopy and biopsy of the esophagus and the findings were recorded in the questionnaire. Results We studied 125 children among whom there were 61 (48.8%) girls and 64 (51.2%) boys with mean age of 6.6±5.5 years. Intractable vomiting was the prominent symptom in our series being reported by 75 (60%) patients followed by fever in 35 (28%). Erythema (33.6%), esophageal ulcer (11.2%), and whitish patch (8.0%) were the most common endoscopic findings while reflux esophagitis (32.8%), chronic (6.4%) and acute esophagitis (5.6%), and candida esophagitis (5.6%) were the most common histological diagnoses. Just 1 (0.8%) patient was diagnosed as having eosinophilic esophagitis, aspergillosis, and graft versus host disease. Conclusion Reflux is the most common cause of esophagitis in the pediatric population of southern Iran. Despite previous rep...

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