6-O-α-(4-O-α-d-glucuronyl)-d-glucosyl-β-cyclodextrin: solubilizing ability and some cellular effects

Tavornvipas, Sumitra; Hirayama, Fumitoshi; Arima, Hisatomi; Uekama, Kaneto; Ishiguro, Tohru; Oka, Masahisa; Hamayasu, Kenichi; Hashimoto, Hitoshi

doi:10.1016/s0378-5173(02)00537-9

Cited by 36 publications

(14 citation statements)

References 16 publications

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“…Some reports29, 32 have shown that when using the lipophilic vehicle IPM, the SC did not seem to offer significant resistance although the viable ED is the rate‐limiting barrier for the transport of relatively hydrophobic drugs. FP is lipophilic and practically insoluble in water (i.e., 0.14 mM33), indicating that IPM as a vehicle is fit to use in research.…”

Section: Resultsmentioning

confidence: 99%

Clinical significance of elevated spleen tyrosine kinase expression in nasopharyngeal carcinoma

Kou²,

Wang

et al. 2012

Head & Neck

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Section: Resultsmentioning

confidence: 99%

Clinical significance of elevated spleen tyrosine kinase expression in nasopharyngeal carcinoma

Kou²,

Wang

et al. 2012

Head & Neck

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“…Among these CDs, β-Cyclodextrin (β-CD) has been chosen for this study since its cavity size is suitable for guest molecules with molecular weights between 200 and 800 g/mol [7,8]. β-CD can accommodate variety of organic and inorganic compounds to form inclusion complexes (ICs) due to its hydrophobic cavity [9,10] thus it is being widely used in pharmaceutical industry [11], foodstuff [12,13], separation studies [14] and environmental engineering [15,16]. …”

Section: Introductionmentioning

confidence: 99%

Conventional Study on Novel Dicationic Ionic Liquid Inclusion with β-Cyclodextrin

Mohamad

Surikumaran

Raoov

et al. 2011

IJMS

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This study focuses on the synthesis and characterization of the inclusion complex of β-Cyclodextrin (β-CD) with dicationic ionic liquid, 3,3′-(1,4-Phenylenebis [methylene]) bis(1-methyl-1H-imidazol-3-ium) di(bromide) (PhenmimBr). The inclusion complex was prepared at room temperature utilizing conventional kneading technique. Proton (1H) NMR and 2D (1H–1H) COSY NMR were the primary characterization tools employed to verify the formation of the inclusion complex. COSY spectra showed strong correlations between protons of imidazolium and protons of β-CD which indicates that the imidazolium ring of PhenmimBr has entered the cavity of β-CD. UV absorption indicated that β-CD reacts with PhenmimBr to form a 2:1 β-CD-PhenmimBr complex with an apparent formation constant of 2.61 × 105 mol&−2 L2. Other characterization studies such as UV, FT-IR, XRD, TGA, DSC and SEM studies were also used to further support the formation of the β-CD-PhenmimBr inclusion complex.

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“…Several weak forces, including van der Waals, hydrophobic, dipole-dipole, and hydrogen bonding interactions, cooperatively determine the inclusion complex behaviour of the CD host [3,4]. Thus CDs have been widely used in pharmaceutical industry [5], foodstuff [6,7], separation technique [8,9], environmental protection [10,11], and so on.…”

Section: Introductionmentioning

confidence: 99%

Interaction of naproxen with β-cyclodextrin and its derivatives/polymer: experimental and molecular modeling studies

Banik

Gogoi

Saikia

2011

J Incl Phenom Macrocycl Chem

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The interaction of naproxen with b-cyclodextrin and its derivatives (hosts) as well as polymer has been studied using UV Visible (UV-Vis), Fourier Transform Infrared (FTIR), Nuclear Magnetic Resonance (NMR) spectroscopy and Scanning electron microscopy (SEM). In this paper, the solid inclusion complexes were prepared by freeze drying method. The formation constants of the complexes were determined by UV-Vis method. The adsorption properties of naproxen with b-Cyclodextrin bonded silica stationary phase (CDS) were studied for an in-depth understanding of the host-guest interaction. The inclusion process involving naproxen and hosts was investigated by using the PM3 quantum-mechanical semiempirical method. The stabilization energy values obtained from the semiempirical calculation showed the same relation with the formation constant values determined by UV-Vis spectroscopy.

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6-O-α-(4-O-α-d-glucuronyl)-d-glucosyl-β-cyclodextrin: solubilizing ability and some cellular effects

Cited by 36 publications

References 16 publications

Clinical significance of elevated spleen tyrosine kinase expression in nasopharyngeal carcinoma

Clinical significance of elevated spleen tyrosine kinase expression in nasopharyngeal carcinoma

Conventional Study on Novel Dicationic Ionic Liquid Inclusion with β-Cyclodextrin

Interaction of naproxen with β-cyclodextrin and its derivatives/polymer: experimental and molecular modeling studies

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