4′ DIPHENYLPHOSPHINO AND BROMO DERIVATIVES OF 10-PHENYL-1,4,7-TRITHIA-10-AZA-CYCLODODECANE 4-R- C₆H₄ N(CH₂CH₂S)₂CH₂CH₂SCH₂CH₂

Anion effects in selective bifunctional metal salt extractants based on aza-thioether macrocycles: co-operative cation–anion binding?

“…1, 3 Their ability to behave as selective metal extraction agents for 'soft' metal ions such as mercury 4 has also been reported. In contrast to pure thioether macrocycles, the chemistry of aza-thioether macrocycles has been relatively neglected, although the parent macrocycles [9]aneNS 2 , 5 [15]aneNS 4 , 6 [12]aneN 2 S 2 7 and several other mixed-donor macrocycles 8 have been reported. In addition, a number of N-aryl substituted aza-thioether macrocycles are known, some of which demonstrate selective Ag  extraction and transport.…”

“…In addition, a number of N-aryl substituted aza-thioether macrocycles are known, some of which demonstrate selective Ag  extraction and transport. 9 Incorporation of a secondary amine group directly into the thioether macrocyclic ring allows facile functionalisation and this is where our interest in these molecules originates. Combining the ability of thioether macrocycles to co-ordinate 'soft' metal ions, even under acidic conditions, with anion binding sites allows the potential preparation of bifunctional molecules for the binding and extraction of metal salts.…”