2016
DOI: 10.1002/jbm.a.35871
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3D printing of PLGA scaffolds for tissue engineering

Abstract: We proposed a novel method of generation of bioresorbable polymeric scaffolds with specified architectonics for tissue engineering using extrusion three-dimensional (3D) printing with solutions of polylactoglycolide in tetraglycol with their subsequent solidifying in aqueous medium. On the basis of 3D computer models, we obtained the matrix structures with interconnected system of pores ranging in size from 0.5 to 500 µm. The results of in vitro studies using cultures of line NIH 3Т3 mouse fibroblasts, floatin… Show more

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Cited by 58 publications
(36 citation statements)
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“…They do not display toxic side effects when being used in the pharmaceuticals and biological materials, with the exception of lactose deficiency. PLGAs are extremely thermolabile compounds When being processed at a heightened temperature, they may provoke the formation of toxic components and structural cross‐linking which in turn causes their unpredictable behavior in the recipient's body …”
Section: Biomaterials For Dental 3d Printingmentioning
confidence: 99%
“…They do not display toxic side effects when being used in the pharmaceuticals and biological materials, with the exception of lactose deficiency. PLGAs are extremely thermolabile compounds When being processed at a heightened temperature, they may provoke the formation of toxic components and structural cross‐linking which in turn causes their unpredictable behavior in the recipient's body …”
Section: Biomaterials For Dental 3d Printingmentioning
confidence: 99%
“…3D printing is as ground-breaking fabrication process o®ering innovative solutions in variety of¯elds including tissue engineering, 172,173 cancer therapy 174 and generation of arti¯cial organ. 175 3D printing combined with advanced techniques of material design and fabrication is even capable to fabricate materials for arti¯cial sca®olds for bone reconstruction and regeneration.…”
Section: Bp For 3d Printing Sca®oldsmentioning
confidence: 99%
“…Recently, biocompatible PLGA scaffolds have been produced using 3D printing for use in tissue engineering [106]. Electrospun PLGA-based hybrid nano-fibrous membranes and scaffolds have been widely used for skin, bone, nerve, and soft tissue engineering applications [105].…”
Section: Polylactic-co-glycolic Acidmentioning
confidence: 99%