Infantile transient smooth muscle contraction of the skin: a case report and literature review

Infantile transient smooth muscle contraction of the skin in a 1-month-old girl

“… 1 One report noted moderate hyperplasia of dermal smooth muscle bundles on histopathologic exam. 5 Although we did not pursue a biopsy for our patient, we suspect our patient would similarly have no abnormalities on skin biopsy. To date, there have been no long-term sequelae or negative health outcomes related to this condition reported, and the episodes of transient contractions resolve by the age of 2 in most children.…”

“… 1 Primarily healthy infants, both male and female, seem to develop this condition within the first few weeks of life and experience diminishing frequency of these episodes over time, contrary to a focal and persistent CSMH. 1 , 5 , 6 , 7 Infantile transient smooth muscle contraction of the skin has been noted in several reports to favor the lower extremities, for reasons unknown. 1 , 7 The episodes usually last seconds to minutes with normal-appearing skin between episodes.…”

“… 1 Consistent with the observation from our patient’s mother, triggers for the transient smooth muscle contraction include air, friction, bathing, and cold temperature. 1 , 5 Infants with transient smooth muscle contraction of the skin appear to have no abnormalities of the skin or the dermal smooth muscle bundles on biopsy. 1 One report noted moderate hyperplasia of dermal smooth muscle bundles on histopathologic exam.…”

Intermittierendes Zittern der Haut bei Neugeborenen und Kleinkindern – ein Grund zur Sorge?

“…2 Bisher wurden in der Literatur 14 Fälle beschrieben. [1][2][3][4][5][6] Als auslösende Faktoren für das Hautzittern wurden Wechseln der Windeln, sanfte Reibung, (kühle) Luftzüge und das Baden beschrieben. Das Phänomen wird aber auch ohne offensichtliche Reize beobachtet.…”

“…Das Phänomen wird aber auch ohne offensichtliche Reize beobachtet. [2][3][4][5][6] Die Ätiologie der infantilen TSMCS ist nicht vollständig geklärt. Die in der Literatur diskutierten Hypothesen beinhalten eine Unreife des autonomen Nervensystems, welche zu einer episodischen Kontraktion der glatten Muskelfasern der Musculi arrectores pilorum führt, eine zeitweise Hypersensitivität der glatten Muskulatur oder ein primitiver Reflex.…”