2021
DOI: 10.1186/s12903-021-01456-9
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Abstract: Background The role of injectable platelet rich fibrin (i-PRF) in orthodontic treatment has not been investigated with focus on its effect on dental and bony periodontal elements. Objective To evaluate the efficacy of i-PRF in bone preservation and prevention of root resorption. Methods A randomized split-mouth controlled trial included 21 patients aged 16–28 years (20.85 ± 3.85), who were treated for … Show more

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Cited by 16 publications
(31 citation statements)
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“…[ 3 ] Studies recently suggested utilizing pharmacologic therapy, biomaterial, and the chewing force in an attempt to provide another mechanism to enhance the stability of teeth after orthodontic treatment. [ 4 5 6 7 ]…”
Section: Introductionmentioning
confidence: 99%
See 2 more Smart Citations
“…[ 3 ] Studies recently suggested utilizing pharmacologic therapy, biomaterial, and the chewing force in an attempt to provide another mechanism to enhance the stability of teeth after orthodontic treatment. [ 4 5 6 7 ]…”
Section: Introductionmentioning
confidence: 99%
“…[ 13 ] Thus, it showed many application in the dental and medical fields with a high rate of success but because of its solid nature, it is used in the orthodontic field remain as a subject of study. [ 6 ]…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…PRF consists of a three-dimensional polymerised autologous fibrin matrix with the incorporation of platelets, growth factors, cytokines, circulating stem cells, and a small number of leukocytes, which play key roles in haemostasis and wound healing. 6,24 PRF releases autologous growth factors gradually and progressively, resulting in a stronger and more persistent effect on cell proliferation, differentiation, migration and matrix synthesis by binding to specific receptors. 10 In addition, PRF could serve as a scaffold to support the migrating conjunctival and endothelial cells.…”
Section: Discussionmentioning
confidence: 99%
“…Excessive contact between the roots and the cortical plates of the alveolus may lead to excessive root resorption. Bucco-lingual root movement [1] may create alveolar bone dehiscence, fenestration, and gingival recession. Torque in patients with thin cortical bone, buccally displaced canines, old extraction sites, and extraction cases require special consideration.…”
Section: Introductionmentioning
confidence: 99%