Beta-blockers versus placebo or no intervention for primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis

Cifuentes, Lorena; Gattini, Daniela; Torres‐Robles, Romina; Gana, Juan Cristóbal

doi:10.1002/14651858.cd011973.pub2

Cited by 8 publications

(2 citation statements)

References 73 publications

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“…43 Larger gastroesophageal varices or gastric varices may be treated by ligation or sclerotherapy; there is no conclusive evidence to support the use of nonselective β-blockers. 44 In cases of acute hemorrhage, the patient typically undergoes endoscopic intervention (ligation or sclerotherapy) and aggressive medical management with blood, nonselective β-blockers, somatostatin analogs, and Sengstaken-Blakermore tube if necessary. 21 For patients who do not respond to initial management or those with high risk of recurrent bleeding, more definitive therapy should be pursued.…”

Section: Interventions For Portal Hypertensionmentioning

confidence: 99%

Liver Interventions in Children

Srinviasan,

Acord,

Lambert

et al. 2023

Digestive Disease Interventions

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This review provides a comprehensive summary of the role of the interventional radiologist in managing liver disorders in children. Interventions are discussed with focus on indications for procedure, technical aspects, and patient management. Recommendations are supported by the most recent evidence and practice experience of the authors in the four subtopics, such as interventions in the post–liver transplant setting, for portal hypertension, for liver tumors, and for vascular anomalies of the liver, with emphasis on congenital portosystemic shunts.

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Section: Interventions For Portal Hypertensionmentioning

confidence: 99%

Liver Interventions in Children

Srinviasan,

Acord,

Lambert

et al. 2023

Digestive Disease Interventions

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“…[4][5][6][7] Guidelines on the diagnosis and management of variceal hemorrhage in children with cirrhosis, while controversial, have been the subject of numerous reviews and will not be reviewed here; we refer readers to the references provided for additional information on this topic. [8][9][10][11][12][13] However, there is a paucity of literature on approaches to the diagnosis and management of other complications of PHTN in children with cirrhosis. The aim of this review is to summarize the current guidelines on the diagnosis and management of complications of cirrhotic PHTN in adults and present the most recent data in pediatrics.…”

mentioning

confidence: 99%

Beyond Varices: Complications of Cirrhotic Portal Hypertension in Pediatrics

et al. 2022

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Complications of cirrhotic portal hypertension (PHTN) in children are broad and include clinical manifestations ranging from variceal hemorrhage, hepatic encephalopathy (HE), ascites, spontaneous bacterial peritonitis (SBP), and hepatorenal syndrome (HRS) to less common conditions such as hepatopulmonary syndrome, portopulmonary hypertension, and cirrhotic cardiomyopathy. The approaches to the diagnosis and management of these complications have become standard of practice in adults with cirrhosis with many guidance statements available. However, there is limited literature on the diagnosis and management of these complications of PHTN in children with much of the current guidance available focused on variceal hemorrhage. The aim of this review is to summarize the current literature in adults who experience these complications of cirrhotic PHTN beyond variceal hemorrhage and present the available literature in children, with a focus on diagnosis, management, and liver transplant decision making in children with cirrhosis who develop ascites, SBP, HRS, HE, and cardiopulmonary complications.

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