Clinical and radiographic comparison of platelet-rich fibrin and mineral trioxide aggregate as pulpotomy agents in primary molars

Patidar, Surendra; Kalra, Namita; Khatri, Amit; Tyagi, Rishi

doi:10.4103/jisppd.jisppd_178_17

Cited by 10 publications

(1 citation statement)

References 2 publications

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“…PRF, which is used in this study, is a cost-effective means of performing vital pulp therapy but the blood withdrawal makes it a limitation in pediatric patients. A study conducted by Surendra et al [ 20 ] has shown a success rate of 92% with PRF, which is less than that of this study.…”

Section: Discussioncontrasting

confidence: 85%

A clinical and radiographic comparison of platelet-rich fibrin and lyophilized platelet-derived preparation as pulpotomy agent in primary molars

et al. 2020

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A BSTRACT Introduction: Vital pulpotomy in primary molar teeth is aimed to retain the tooth in function until it is replaced by its successors. Aim: The aim of this study was to evaluate and compare platelet-rich fibrin (PRF) and lyophilized platelet-derived preparation (LPDP) as a pulpotomy agent in primary molars. Materials and Methods: Forty primary molars from 20 healthy children aged 5–9 years requiring pulpotomy in the contralateral side of mandible were randomly selected. In both the groups, pulpotomy was carried out by removing coronal pulp and achieving hemostasis, the radicular part of pulp tissue was packed with PRF preparation in Group I and LPDP (Mothercell Research Centre, Trichy, Tamil Nadu, India) in Group II. The teeth were restored with zinc oxide eugenol and glass ionomer cement (GIC), followed by stainless steel crown in the same visit. Clinical and radiographic evaluation was undertaken at 1, 3, and 6 months interval. Results: The overall success rate was 90% in PRF group and 95% in LPDP group at the end of 6 months. The results were statistically nonsignificant between the groups ( P > 0.05). Conclusion: The overall outcome of the study suggests that PRF and LPDP are acceptable pulpotomy agents and are promising in the era of new vital pulp therapy procedure.

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Section: Discussioncontrasting

confidence: 85%

A clinical and radiographic comparison of platelet-rich fibrin and lyophilized platelet-derived preparation as pulpotomy agent in primary molars

et al. 2020

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Efficacy of Alternative Medicaments for Pulp Treatment in Primary Teeth in the Short Term: A Meta-analysis

Park

Jasani

Patel

et al. 2019

Journal of Evidence Based Dental Practice

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Objective: This systematic review and meta-analysis aimed to evaluate the overall, clinical, and radiographical success rates of alternative pulpotomy medicaments in primary teeth. Methods: A systematic search of five databases was conducted following the PRISMA guidelines. Prospective clinical trials utilising alternative pulpotomy medicaments in children were included. The outcome measures were overall, clinical, and radiographic success, expressed in percentages and converted to odds ratios (OR). Fifteen articles were included in the meta-analysis. Results: combined OR for overall, clinical, and radiographic success was 0.55 [95% CI: 0.12-2.41; P=0.42; I 2 =76%], 1.03 [95% CI: 0.57-1.86; P= 0.92; I 2 =0%] and 0.84 [95% CI: 0.54-1.47; P=0.66; I 2 =34%], respectively. The results suggest an inconclusive outcome in the success rate of alternative medicaments. Conclusions: There is insufficient evidence to support the efficacy of alternative pulpotomy medicaments for use in primary teeth. Further robust studies are required before such alternative medicaments should be used in clinical practice.

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Clinical Application of Platelet-Rich Fibrin in Pediatric Dentistry

Gunasekaran

Sakthivel

Shanthala

et al. 2021

Journal of Health and Allied Sciences NU

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Platelet-rich fibrin (PRF) is a fibrin matrix in which platelet cytokines, growth factors, and cells are trapped and may be released after a certain time and that can serve as a resorbable membrane. It can be obtained from blood with the help of a simple process. PRF is basically a concentrate of growth factors that promote wound healing and regeneration, which is used in various disciplines of dentistry to repair various lesions and regenerate dental and oral tissues. Although the use of PRF is well-documented, its use in pediatric dentistry remains unexplored, due to its restrictions and on account of the fact that it is a blood-derived product. PRF has been used globally to enhance tissue healing. This article provides an insight into the use of PRF in pediatric dentistry, its benefits, limitations, and recommendations.

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Clinical and radiographic comparison of platelet-rich fibrin and mineral trioxide aggregate as pulpotomy agents in primary molars

Abstract: Radiographic and clinical outcome in PRF group could suggest it as an acceptable alternative in pulpotomy of primary teeth. PRF holds a promising future in the area of primary tooth vital pulp therapy.

Cited by 10 publications

References 2 publications

A clinical and radiographic comparison of platelet-rich fibrin and lyophilized platelet-derived preparation as pulpotomy agent in primary molars

A clinical and radiographic comparison of platelet-rich fibrin and lyophilized platelet-derived preparation as pulpotomy agent in primary molars

Efficacy of Alternative Medicaments for Pulp Treatment in Primary Teeth in the Short Term: A Meta-analysis

Clinical Application of Platelet-Rich Fibrin in Pediatric Dentistry

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