2016
DOI: 10.1002/14651858.cd011980.pub2
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Abstract: There is no evidence from RCTs to determine what is the correct platelet transfusion threshold prior to insertion of a lumbar puncture needle or epidural catheter. There are no ongoing registered RCTs assessing the effects of different platelet transfusion thresholds prior to the insertion of a lumbar puncture or epidural anaesthesia in people with thrombocytopenia. Any future RCT would need to be very large to detect a difference in the risk of bleeding. We would need to design a study with at least 47,030 pa… Show more

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Cited by 15 publications
(4 citation statements)
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References 46 publications
(66 reference statements)
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“…In agreement with a recent publication, these variables did not reach significance in our study 32 . A Cochrane systematic review found that there was no evidence for a difference in the risk of minor bleeding in participants who received platelet transfusions and those who did not before a lumbar puncture 33 .…”
Section: Discussionmentioning
confidence: 99%
“…In agreement with a recent publication, these variables did not reach significance in our study 32 . A Cochrane systematic review found that there was no evidence for a difference in the risk of minor bleeding in participants who received platelet transfusions and those who did not before a lumbar puncture 33 .…”
Section: Discussionmentioning
confidence: 99%
“…Las alteraciones en la hemostasia aparecen especialmente en el contexto de síndrome HELLP (síndrome de hemólisis, elevación de enzimas hepáticas, trombocitopenia) que cursa con hemólisis (LDH > 600 U/L), trombocitopenia (plaquetas < 150.000/mm 3 ) y elevación de AST ≥ 70 U/L [17], [19], [20].…”
Section: Generalidades Preeclampsiaunclassified
“…We thank Callum Ingram, Simon Stanworth and Marialena Trivella, who were authors on the original review (Estcourt 2016).…”
Section: Acknowledgementsmentioning
confidence: 99%
“…Because we found no eligible randomised controlled trials for inclusion in the previous version of the review (Estcourt 2016), we felt there was a particular need to expand the review scope and examine other study types to aid in answering the review question. We amended the review Methods to accommodate the inclusion of non-randomised studies in order to reflect these changes.…”
Section: Characteristics Of Included Studies [Ordered By Study Id]mentioning
confidence: 99%