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Cited by 5 publications
(3 citation statements)
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References 14 publications
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“…NEFA may not be purely beneficial. Albumin resuscitation is reported to increase albumin leakage into extravascular space (24). However, we saw no decrease in total vascular albumin after Plasmalyte or FA-free BSA, suggesting that vasculature did not become leaky to larger molecules from hemorrhagic shock alone or from albumin resuscitation.…”
Section: Compensatory Mechanismscontrasting
confidence: 51%
“…NEFA may not be purely beneficial. Albumin resuscitation is reported to increase albumin leakage into extravascular space (24). However, we saw no decrease in total vascular albumin after Plasmalyte or FA-free BSA, suggesting that vasculature did not become leaky to larger molecules from hemorrhagic shock alone or from albumin resuscitation.…”
Section: Compensatory Mechanismscontrasting
confidence: 51%
“…Notably, an exploratory study of trauma patients monitored with pulmonary artery catheter confirmed that colloids increased volaemia and cardiac output more significantly than crystalloids [88]. However, in the RCTs comparing colloids and crystalloids, the subgroup analyses of trauma patients did not reveal any reduction of patient outcomes, including 28-day or 90-day mortality [28] or transfusion requirements [89]. Thus, isotonic crystalloid solutions rather than colloids are recommended for the initial resuscitation of bleeding trauma patients [87].…”
Section: Trauma Patientsmentioning
confidence: 99%
“…In humans, an exploratory study of patients monitored with a pulmonary artery catheter showed similar hemodynamic outcomes with a lower volume of colloids than crystalloids [93]. However, subgroup analyses of trauma patients included in the RCTs comparing colloids and crystalloids have since failed to confirm this assumption with regards to wither mortality [48] or transfusion requirements [94]. In patients with TBI, mortality was actually higher with albumin than with saline, probably due to the greater increase in intracranial pressure observed during administration of albumin [95].…”
Section: Methodsmentioning
confidence: 99%