21-Day Dry Immersion: Design and Primary Results

Tomilovskaya, Elena; Rukavishnikov, Ilya; Amirova, Liubov; Shigueva, Tatiana; Saveko, Alina; Kitov, Vladimir; Vasilieva, G. Yu.; Ponomarev, Sergey; Смирнова, Т. А.; Kozlovskaya, I. B.; Орлов, О. И.

doi:10.21687/0233-528x-2020-54-4-5-14

Cited by 4 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Data obtained from previous DI experiments (3–21 days) demonstrated that back pain sensations - described as blunt aching, mainly in the upper lumbar spine region ( Rukavishnikov et al, 2017 ; Tomilovskaya et al, 2020 ) were observed during the first 36 h in DI ( Rukavishnikov et al, 2017 ; Treffel et al, 2017 )—again broadly consistent with that reported by some crew ( Pool-Goudzwaard et al, 2015 ) during early spaceflight ( Kertsman et al, 2012 ). A decrease in myofascial tissue tone, spinal elongation, and the development of LBP does not necessarily correlate in time.…”

Section: Discussionsupporting

confidence: 83%

“…Thus, the sensation of pain requires a longer time to develop than physical changes. LBP observed in previous studies (Rukavishnikov et al, 2017;Tomilovskaya et al, 2020) has only peaked after 12-24 h h of unloading. This could suggest that time spent in the bath was insufficient for triggering sufficient physical changes to provoke more intense pain in the back.…”

Section: Low Back Painmentioning

confidence: 59%

See 1 more Smart Citation

Dry immersion induced acute low back pain and its relationship with trunk myofascial viscoelastic changes

et al. 2022

View full text Add to dashboard Cite

Microgravity induces spinal elongation and Low Back Pain (LBP) but the pathophysiology is unknown. Changes in paraspinal muscle viscoelastic properties may play a role. Dry Immersion (DI) is a ground-based microgravity analogue that induces changes in m. erector spinae superficial myofascial tissue tone within 2 h. This study sought to determine whether bilateral m. erector spinae tone, creep, and stiffness persist beyond 2 h; and if such changes correlate with DI-induced spinal elongation and/or LBP.Ten healthy males lay in the DI bath at the Institute of Biomedical Problems (Moscow, Russia) for 6 h. Bilateral lumbar (L1, L4) and thoracic (T11, T9) trunk myofascial tone, stiffness and creep (MyotonPRO), and subjective LBP (0-10 NRS) were recorded before DI, after 1h, 6 h of DI, and 30min post. The non-standing spinal length was evaluated on the bath lifting platform using a bespoke stadiometer before and following DI.DI significantly modulated m. erector spinae viscoelastic properties at L4, L1, T11, and T9 with no effect of laterality. Bilateral tissue tone was significantly reduced after 1 and 6 h DI at L4, L1, T11, and T9 to a similar extent. Stiffness was also reduced by DI at 1 h but partially recovered at 6 h for L4, L1, and T11. Creep was increased by DI at 1 h, with partial recovery at 6 h, although only T11 was significant. All properties returned to baseline 30 min following DI. Significant spinal elongation (1.17 ± 0.20 cm) with mild (at 1 h) to moderate (at 6 h) LBP was induced, mainly in the upper lumbar and lower thoracic regions. Spinal length increases positively correlated (Rho = 0.847, p = 0.024) with middle thoracic (T9) tone reduction, but with no other stiffness or creep changes. Spinal length positively correlated (Rho = 0.557, p = 0.039) with Max LBP; LBP failed to correlate with any m. erector spinae measured parameters.The DI-induced bilateral m. erector spinae tone, creep, and stiffness changes persist beyond 2 h. Evidence of spinal elongation and LBP allows suggesting that the trunk myofascial tissue changes could play a role in LBP pathogenesis observed in real and simulated microgravity. Further study is warranted with longer duration DI, assessment of IVD geometry, and vertebral column stability.

show abstract

Section: Discussionsupporting

confidence: 83%

Section: Low Back Painmentioning

confidence: 59%

Dry immersion induced acute low back pain and its relationship with trunk myofascial viscoelastic changes

et al. 2022

View full text Add to dashboard Cite

show abstract

“…As studies conducted earlier in men show, an increase in body height occurs in the first day of immersion, and then remains at this level throughout the entire exposure. Under conditions of 21-day DI, the average height in men increases by 2 cm (Tomilovskaya et al, 2020). In our study, women did not show a significant increase in height, which may be due to the greater plasticity of women's connective tissue.…”

Section: Comparison Of Bed Rest and Dry Immersion Studycontrasting

confidence: 68%

“…During Dry Immersion experiments in women, we noted a distinct trait that was not observed (or expressed to a much lesser extent) in men ( Tomilovskaya et al, 2020 ). All women in the group noted some problems with urination expressed in the urge to urinate without the possibility of its fulfillment.…”

Section: Resultsmentioning

confidence: 69%

The First Female Dry Immersion (NAIAD-2020): Design and Specifics of a 3-Day Study

et al. 2021

View full text Add to dashboard Cite

This article describes procedures and some results of the first study of females undergoing 3-day Dry Immersion. The experiment “NAIAD-2020” was carried out at the Institute of Biomedical Problems (Moscow, Russia) with the participation of six healthy women volunteers (age 30.17 ± 5.5 years, height 1.66 ± 0.1 m, weight 62.05 ± 8.4 kg, BMI 22.39 ± 2.2 kg/m2) with a natural menstrual cycle. During the study, a standard protocol was used, the same as for men, with a minimum period of time spent outside the immersion bath. Before, during and after Immersion, 22 experiments were carried out aimed at studying the neurophysiological, functional, metabolic and psychophysiological functions of the body, the results of which will be presented in future publications. The total time outside the bath for women did not exceed that for men. Systolic and diastolic pressure did not significantly change during the immersion. In the first 24 h after the end of the immersion, heart rate was significantly higher than the background values [F(4,20) = 14.67; P < 0.0001]. Changes in body temperature and water balance were consistent with the patterns found in men. No significant changes in height and weight were found during immersion. All women reported general discomfort and pain in the abdomen and back. The results of this study did not find significant risks to women’s health and showed the feasibility of using this model of the effects of space flight in women of reproductive age.

show abstract

“…At this point, our data is in line with previous observations on morphological changes in the spine occurring at the first 3–4 days of DI ( Kozlovskaya et al, 2015 ; Treffel et al, 2020 ). Some participants also experienced abdominal pain due to stool retention ( Poliakov et al, 2020 ; Tomilovskaya et al, 2020 ). All this can provoke a lengthening of sleep latency and unstable, restless sleep with frequent awakenings.…”

Section: Discussionmentioning

confidence: 99%

Sleep in 21-Day Dry Immersion. Are Cardiovascular Adjustments Rapid Eye Movement Sleep-Dependent?

et al. 2021

View full text Add to dashboard Cite

Introduction: A decrease in sleep quality and duration during space missions has repeatedly been reported. However, the exact causes that underlie this effect remain unclear. In space, sleep might be impacted by weightlessness and its influence on cardiovascular function. In this study, we aimed at exploring the changes of night sleep architecture during prolonged, 21-day Dry Immersion (DI) as one of the ground-based models for microgravity studies and comparing them with adaptive changes in the cardiovascular system.Methods: Ten healthy young men were exposed to DI for 21 days. The day before (baseline, B-1), on the 3rd (DI3), 10th (DI10), and 19th (DI19) day of DI, as well as in the recovery period, 1 day after the end of DI (R + 1), they were subjected to overnight polysomnography (PSG) and ambulatory blood pressure monitoring.Results: On DI3, when the most severe back pain occurred due to the effects of DI on the spine and back muscles, the PSG data showed dramatically disorganized sleep architecture. Sleep latency, the number of awakenings, and the duration of wake after sleep onset (WASO) were significantly increased compared with the B-1. Furthermore, the sleep efficiency, duration of rapid eye movement sleep (REM), and duration of non-rapid eye movement stage 2 decreased. On DI10, subjective pain ratings declined to 0 and sleep architecture returned to the baseline values. On DI19, the REM duration increased and continued to rise on R + 1. An increase in REM was accompanied by rising in a nighttime heart rate (HR), which also shows the most significant changes after the end of DI. On DI19 and R + 1, the REM duration showed opposite correlations with the BP parameters: on DI19 it was negatively associated with the systolic BP (SBP), and on R + 1 it was positively correlated with the diastolic BP (DBP).Conclusion: An increase in REM at the end of DI and in recovery might be associated with regulatory changes in the cardiovascular system, in particular, with the reorganization of the peripheral and central blood flow in response to environmental changes.

show abstract

21-Day Dry Immersion: Design and Primary Results

Cited by 4 publications

References 0 publications

Dry immersion induced acute low back pain and its relationship with trunk myofascial viscoelastic changes

Dry immersion induced acute low back pain and its relationship with trunk myofascial viscoelastic changes

The First Female Dry Immersion (NAIAD-2020): Design and Specifics of a 3-Day Study

Sleep in 21-Day Dry Immersion. Are Cardiovascular Adjustments Rapid Eye Movement Sleep-Dependent?

Contact Info

Product

Resources

About