2,5 Dihydroxyphenylpyruvic Acid in Human Urine

Skin and Muscle Indurations in Phenylketonuria

“…In our patient, 2,5-DHPPA could not be demonstrated, although the standards pre¬ pared in our laboratory corresponded in all respects to those of Nishimura et al17-18 and Yee et al 25 However, it may be present only periodically, and failure to demonstrate it is not proof of its absence. Possibly, some part is played here by certain secondary disturb¬ ances, due to accumulation of abnormal PHA metabolites and involving the oxidases needed for the conversion of phenylpyruvic and p-hydroxyphenylpyruvic acids to 2,5-DHPPA.…”

Pathophysiology of Scleroderma—A Review

“….~ Ings have been confirmed by some gioups 29 The possibility that dysfunctio n of the parathyro id glands was of etiologic significanc e in scleroderm a constitute d the rationale for the extirpatio n 4 o of these glands in the treatment of this disease. Although some favorable re-sults4o have been observed, the accumu-Iated experience 1 with this form of therapy has been disappoin ting and it is no longer considered of value.…”

An N-Methylpyrrolidone-Diacetylene Complex. Its Use in the Isolation of Diacetylene

“…Anal. Caled, for Ci2H13NQ2: C, 70.91; H,6.45; N, 6.89. Found: C, 70.63; H, 6.76; N, 6.94. 3-Aryl-4-methylene-5,5-dimethyloxazolidine-2-one (from 3-Hydroxy-3-methyl-2-butanone. )-One-tenth mole of aryl isocyanate was added slowly to 10 g. (0.10 mole) of 3-hydroxy-3-methyl-2-butanone with swirling.…”