18F-FDG PET/CT Findings in Metastatic Pilomatrix Carcinoma

Şengöz, Tarık; Avcı, Nilüfer

doi:10.1097/rlu.0000000000002857

Clin Nucl Med

2019

DOI: 10.1097/rlu.0000000000002857

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18F-FDG PET/CT Findings in Metastatic Pilomatrix Carcinoma

Tarık Şengöz

Nilüfer Avcı

Abstract: We describe a rare case of metastatic pilomatrix carcinoma with distant metastases 10 months after diagnosis. A 37-year-old woman was diagnosed with pilomatrix carcinoma by excisional biopsy from the occipital region and referred to us for 18F-FDG PET/CT examinations at the time of diagnosis and 10 months after diagnosis. The first PET/CT did not show any pathological activity, whereas the second PET/CT showed multiple intensive 18F-FDG uptakes in the right lung parenchyma, right hemithorax pleura, liver, and … Show more

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“…In our case, LCH involved only the pleura. Mesothelioma, 12 metastasis, 13 lymphoma, 14 nocardiosis, 15 IgG4-related disease, 16 and malignant nerve sheath tumors 17 can involve the pleura and show abnormal FDG uptake on PET/CT. This case indicates that LCH can be a differential diagnosis when we interpret multiple pleural FDG-avid lesions on PET/CT.…”

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PET/CT Showing a Case of Langerhans Cell Histiocytosis Involving the Pleura

2022

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We describe a case of Langerhans cell histiocytosis involving the bilateral pleura on FDG PET/CT. Multiple pleural nodules were detected by CT in a 38-year-old woman with chest pain and night sweats. Malignant tumors were suspected. PET/CT showed abnormal FDG uptake in those pleural lesions. No other abnormal foci were seen in the rest of the whole body. A primary pleural disease was considered. Then the histopathologic findings after biopsy confirmed the diagnosis of Langerhans cell histiocytosis.

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PET/CT Showing a Case of Langerhans Cell Histiocytosis Involving the Pleura

2022

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Pilomatrix Carcinoma: Report of Two Cases of the Head and Review of the Literature

et al. 2023

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Background: Pilomatrix carcinoma (PC) is a rare skin tumor arising from hair follicle matrix cells. It is locally aggressive with a high rate of local recurrence after surgical excision. Few cases in the literature have been described and the management is not well defined. Objectives: The aim of this study was to present two cases of PC located on the head and review the relevant literature about epidemiology, clinical and dermoscopic evaluation, characteristics of local and distant metastases, local recurrence rate and management of this rare skin tumor. Methods: We consulted databases from PubMed, Research Gate and Google Scholar, from January 2012 to November 2022. We reviewed the literature and reported two additional cases. Results: We selected 52 tumors in middle-aged to older patients located mostly on the head. Dermoscopy evaluation was rarely performed in the pre-operative diagnostic setting. The most definitive treatment was wide local excision, but local recurrences were common. In total, we observed 11 cases of recurrences and 9 patients with locoregional or distant metastases. Four patients received adjuvant radiotherapy, two patients needed chemotherapy and local cancer therapy and one patient received radiochemotherapy. Conclusions: Our reports and the review of the literature can provide a better awareness and management of this rare tumor.

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18F-FDG PET/CT Findings in Metastatic Pilomatrix Carcinoma

Cited by 2 publications

References 7 publications

PET/CT Showing a Case of Langerhans Cell Histiocytosis Involving the Pleura

PET/CT Showing a Case of Langerhans Cell Histiocytosis Involving the Pleura

Pilomatrix Carcinoma: Report of Two Cases of the Head and Review of the Literature

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