Robin Beaven, Ricardo Nunes Bastos, Christos Spanos, Pierre Romé, C. Fiona Cullen, Juri Rappsilber, Régis Giet, Gohta Goshima, Hiroyuki Ohkura
Abstract:14-3-3 interacts with the kinesin-14 Ncd and prevents it from binding microtubules. Aurora B provides a spatial cue that releases Ncd from 14-3-3 around chromosomes, allowing Ncd to selectively bind the spindle microtubules in the large volume of oocytes.
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