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Cited by 20 publications
(21 citation statements)
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“…Similar to the results here described, Santos et al (2020) have shown, for capillary whole blood, a sensitivity of 55% for the Wondfo LFIA test in HCWs. On the other hand, the detection sensitivity in serum samples was much higher (96%).…”
Section: Discussionsupporting
confidence: 89%
See 1 more Smart Citation
“…Similar to the results here described, Santos et al (2020) have shown, for capillary whole blood, a sensitivity of 55% for the Wondfo LFIA test in HCWs. On the other hand, the detection sensitivity in serum samples was much higher (96%).…”
Section: Discussionsupporting
confidence: 89%
“…The use of POC based tests for rapid antibody detection can be helpful in identifying patients at different stages of infection, due to the early production of IgM followed by IgG response, even though in patients with COVID-19 the IgM and IgG response could be simultaneous. Our results demonstrated that overall sensitivity achieved by Bioclin LFIA (85.71%) with whole blood samples is compared to those obtained with serum or plasma, in contrast to Livzon and Wondfo LFIAs which showed sensitivities below 50% (Costa et al, 2020;Santos et al, 2020;Silveira et al, 2020;Tuaillon et al, 2020).…”
Section: Discussionmentioning
confidence: 57%
“…These studies estimated the test’s sensitivity and specificity at 84.8% and 99.0%, respectively. It has been suggested that using capillary blood to estimate seroprevalence tends to increase the rate of false negative results ( 18 ); however, this finding has not been replicated by other studies ( 19 ). Furthermore, our validation study ( 8 ) used capillary blood and the observed sensitivity was similar to that reported in another studies.…”
Section: Discussionmentioning
confidence: 93%
“…This discrepancy is likely accounted for by the lower sensitivity of the assay that was used to test capillary (finger prick) blood. Although the authors corrected for test characteristics, it is likely that the true sensitivity in capillary blood is lower 30 . This highlights the advantage of using the blood donor population, where the infrastructure necessary for the use of state-of-the-art laboratory-based serological assays on blood samples is well established.…”
Section: Discussionmentioning
confidence: 99%