2019
DOI: 10.6061/clinics/2019/e608
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Abstract: OBJECTIVE: The present study aimed to investigate the relationship between obesity and mortality in patients with community-acquired pneumonia (CAP) in China. METHODS: In total, 909 patients with CAP were recruited for this study from January 2010 to June 2015. All patients were selected and divided into 4 groups according to their body mass index (BMI) values. All patients' clinical information was recorded. The associations among mortality; BMI; the 30-day, 6-month an… Show more

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Cited by 7 publications
(7 citation statements)
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“…Supporting this hypothesis for CAP, Corrals-Medina et al [ 174 ] could show that an increased BMI is associated with reduced 30-day mortality; confirmed in a larger sample size via a clinical study by Singanayamagam et al [ 175 ]. Similar results were reported for 1-year [ 176 ] and 6-year mortality rates [ 177 ]. Interestingly, one study also reported higher CRP levels in obese subjects [ 175 ].…”
Section: Pulmonary Infections and The Impact Of Obesitysupporting
confidence: 89%
See 1 more Smart Citation
“…Supporting this hypothesis for CAP, Corrals-Medina et al [ 174 ] could show that an increased BMI is associated with reduced 30-day mortality; confirmed in a larger sample size via a clinical study by Singanayamagam et al [ 175 ]. Similar results were reported for 1-year [ 176 ] and 6-year mortality rates [ 177 ]. Interestingly, one study also reported higher CRP levels in obese subjects [ 175 ].…”
Section: Pulmonary Infections and The Impact Of Obesitysupporting
confidence: 89%
“…This suggests higher levels of inflammation, which were assumed to possibly improve outcomes via immunomodulation in severe cases. In stark contrast, Chen et al [ 176 ] did not observe this effect, but determined CRP levels as one of the seven risk factors besides obesity for increased 1-year mortality and suggested a potential association between those parameters. Singanayamagam et al [ 175 ] further argued that the state of chronic inflammation in obese patients could be a reason for a generally activated state of host defense.…”
Section: Pulmonary Infections and The Impact Of Obesitymentioning
confidence: 92%
“…These findings are very similar to the current data showing that it is possible that patients with diabetes are hospitalized with a less severe disease or that the presence of obesity could explain this lower mortality in patients with diabetes. Several studies have indicated that obesity was not associated with a higher mortality risk during admission for CAP [34][35][36]. A meta-analysis by Nie et al concluded that overweight and obesity were significantly associated with reduced risk of pneumonia mortality (RR 0.83, 95% CI 0.77 to 0.91, p < 0.01) and suggested that an 'obesity survival paradox' exists for pneumonia [34].…”
Section: Discussionmentioning
confidence: 99%
“…Although obesity is associated with increased mortality due to multiple causes[ 16 - 18 ], it is associated with a better prognosis in patients with CAP (the so-called obesity survival paradox)[ 19 - 24 ]. However, conflicting results have been found[ 25 , 26 ], especially regarding the categories of patients at risk of higher mortality.…”
Section: Discussionmentioning
confidence: 99%
“…In a cohort study of 110000 Japanese adults, BMI (≥ 25 kg/m 2 ) had a protective effect on pneumonia mortality [odds ratio (OR) = 0.7, 95% confidence interval (CI): 0.5-0.8][ 21 ]. Thus, in some diseases, obesity has emerged as a protective factor that could improve prognosis and reduce mortality[ 22 - 24 ]. Nevertheless, conflicting results are found in the literature[ 25 , 26 ].…”
Section: Introductionmentioning
confidence: 99%