Relationships between female infertility and female genital infections and pelvic inflammatory disease: a population-based nested controlled study

Xin, Tao; Ge, Shengfang; Chen, Lei; Cai, Lixin; Hwang, Muh-fa; Wang, Chiung-Lang

doi:10.6061/clinics/2018/e364

Cited by 29 publications

(29 citation statements)

References 25 publications

(29 reference statements)

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“…The odds of infertility among women whose menstruation flow was greater than three days were 4.2 times higher than those among women whose menstruation flow was less than or equal to three days. This result is similar to the result of the studies conducted in India [5] and China [19]. This might be related to hormonal disorders.…”

Section: International Journal Of Reproductive Medicinesupporting

confidence: 91%

Determinants of Infertility among Married Women Attending Dessie Referral Hospital and Dr. Misganaw Gynecology and Obstetrics Clinic, Dessie, Ethiopia

Bayu

Egata

Kefale

et al. 2020

International Journal of Reproductive Medicine

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Background. Infertility is the inability to become pregnant after one year of sexual intercourse without the use of contraception. Epidemiological data suggest that 10 to 15% of couples around the world are suffering from infertility. The exact meaning of marriage is mainly fulfilled if the couple conceives and bears children. Failure of this often leads to unhappy married lives, divorces, and high levels of psychiatric morbidity. There is scarcity of data about determinants of infertility in Ethiopia. Therefore, the aim of this study is to identify the determinants of infertility among married women attending Dessie Referral Hospital and Dr. Misganaw gynecology and obstetrics specialty clinic, Dessie, Ethiopia, 2019. Methods. An institution-based case-control study was conducted on 281 participants. The participants were selected by a systematic random sampling technique. Data were collected using a structured interviewer-administered questionnaire. Data were entered into EpiData version 3.1 and exported to SPSS version 23 for analyses. Variables with p<0.25 in bivariable logistic regression were entered into multivariable logistic regression. Odds ratio with its 95% confidence interval was estimated to measure the direction and strength of the association. The level of statistical significance was set at p<0.05. Results. The determinants of women’s infertility were age at the first pregnancy (AOR=2.89; 95% CI: 1.105, 7.564), age at menarche (AOR=3.2; 95% CI: 1.278, 7.975), menstruation flow in days (AOR=4.17; 95% CI: 0.062, 0.929), multiple sexual partners (AOR=5.33; 95% CI: 2.124, 13.397), and history of STI (AOR=2.79; 95% CI: 1.088, 7.159). Conclusion. Age at the first pregnancy, age at menarche, multiple sexual partners, number of days of menstruation flow, and history of STI were determinants of women’s infertility. Infertility may bring about unhappy married lives, divorces, and high levels of psychiatric morbidity. Therefore, couples need to have heath education about risk factors for infertility.

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Section: International Journal Of Reproductive Medicinesupporting

confidence: 91%

Determinants of Infertility among Married Women Attending Dessie Referral Hospital and Dr. Misganaw Gynecology and Obstetrics Clinic, Dessie, Ethiopia

Bayu

Egata

Kefale

et al. 2020

International Journal of Reproductive Medicine

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“…Jika abses ruptur, dapat terjadi sepsis yang mengancam jiwa sehingga kekhawatiran klinis untuk diagnosis ini memerlukan evaluasi dan pengobatan segera. [1][2][3] Abses tubo-ovarium paling sering ditemukan pada wanita usia reproduksi dan hampir 60% wanita dengan TOA adalah nulipara. Sebelum tahun 2002, 20% dari kasus PID yang dirawat di rumah sakit disertai dengan TOA.…”

Section: Pendahuluanunclassified

Tubo-Ovarian Abscess: in Dr. Zainoel Abidin Banda Aceh Hospital: a Case Report

et al. 2020

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Background: Blood transfusion is an important part of modern health services. When used properly, transfusion can save patient’s life and improve health. Blood transfusion has risk of transmitted infectious diseases through blood transfusion (TTI) especially HIV / AIDS, Hepatitis C, Hepatitis B, and Syphilis, and Malaria, Dengue Fever (DHF) can only be done in endemic areas, as well as other transfusions which can be life threatening.Method: This was descriptive study with cross sectional approach and sampling techniques using secondary data with total population method. From the sample of 23,875 samples (12,305 (2017) and 11,573 (2018)), it was seen which results of TTI reactive from donor data to be included in finding research objects. Results: In 2017 HbSAg reactive TTI parameters 1.7%, Anti HCV 0.5%, HIV Ag / Ab 0.7%, and Treponema 4% and TTI reactive results in donors in 2018 HbSAg parameters 1.3%, Anti HCV 0.3%, HIV Ag / Ab 0.25% and Treponema 2.2%. Comparison of donor TTI screening results in Blood Center of North Aceh-Indonesia in the period 2017-2018 changes in the ratio of TTI reactive numbers in the HbSAg parameter of 0.4%, Anti HCV 0.2%, HIV Ag / Ab 0.45% and Treponema 1.8% in period 2018.Conclusion: Although the reactive rate in 2017 is relatively high, in 2018 the reactive TTI level shows a decline. This condition can be caused by two factors. ; (1) Implementation of donor selection was good with good data collection and documentation system. (2) The inspection method carried out affects the results of the existing inspection.

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“…Without timely and thorough treatment PID can cause a series of sequelae including chronic pelvic pain, pelvic adhesion, and infertility [2]. A population-based nested controlled study, which included 18,276 women with a new diagnosis of infertility and 73,104 matched controls, showed PID were associated with an increased risk of infertility in women aged ≤40 years [3]. Reproductive tract infection, especially N. gonorrhoeae and C. trachomatis [4], and uterine cavity operation are the most common causes of PID.…”

Section: Introductionmentioning

confidence: 99%

Fuke Qianjin Combined with Antibiotic Therapy for Pelvic Inflammatory Disease: A Systematic Review and Meta‐Analysis

Chen

Wei

Huang

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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Background. Pelvic inflammatory disease (PID) without timely and proper treatment can cause long-term sequelae; meanwhile, patients will be confronted with the antimicrobial resistance and side effects. Chinese patent medicine as a supplement is used to treat PID with satisfactory clinical efficacy. This study evaluated the efficacy and safety of Fuke Qianjin (FKQJ) combined with antibiotics in the treatment of PID. Methods. Eight electronic databases and other resources were searched to make a collection of the randomized controlled trials (RCTs) from 1990 to 2019. The RCTs contrasting the effect of FKQJ combined with antibiotics regimens and antibiotics alone in reproductive women with PID were included. The antibiotics regimens are all recommended by the guidelines. Two reviewers independently screened the studies, extracted the data, and assessed the methodological quality of the included studies. Then, the meta-analyses were performed by RevMan 5. 3 software if appropriate. Results. Twenty-three RCTs (2527 women) were included in this review. The evidence showed that FKQJ combined with antibiotics improved the markedly effective rate compared to antibiotics alone group (RR = 1.38, 95% CI 1.27 to 1.49, I2 = 42%), shortened the improvement time of low abdominal pain (MD = −1.11, 95% CI −1.39 to −0.84, I2 = 38%), and increased the rate of lower abdominal pain improvement (RR = 1.35, 95% CI 1.19 to 1.55, I2 = 0). The implementation of adjuvant reduced the recurrent rate compared with antibiotics alone (RR = 0.27, 95% CI 0.13 to 0.56, I2 = 0%). Conclusions. Based on available evidence, FKQJ combined with antibiotics therapy have certain outcomes on increasing the markedly effective rate, decreasing the recurrent rate compared with antibiotics alone group. This therapy appears to improve lower abdominal pain and curtail the relief time. Due to the low quality and the risk of bias, any high-quality evidence or longer follow-up period should be advisable and necessary in the future.

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Relationships between female infertility and female genital infections and pelvic inflammatory disease: a population-based nested controlled study

Cited by 29 publications

References 25 publications

Determinants of Infertility among Married Women Attending Dessie Referral Hospital and Dr. Misganaw Gynecology and Obstetrics Clinic, Dessie, Ethiopia

Determinants of Infertility among Married Women Attending Dessie Referral Hospital and Dr. Misganaw Gynecology and Obstetrics Clinic, Dessie, Ethiopia

Tubo-Ovarian Abscess: in Dr. Zainoel Abidin Banda Aceh Hospital: a Case Report

Fuke Qianjin Combined with Antibiotic Therapy for Pelvic Inflammatory Disease: A Systematic Review and Meta‐Analysis

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