“…Novel imaging techniques, such as blood oxygen leveldependent (BOLD) MRI, 52 ultra-small super-paramagnetic iron oxide (USPIO) contrast-enhanced MRI, 53 diffusion tensor imaging, 54 delayed Gd(DTPA) T2 mapping, 55 T2 mapping, 56,57 sodium 58 and quantitative cartilage 59 MRI, 3D ultrasound, 60 microbubble contrast-enhanced US, 61 and positron emission tomography, 62 require further investigation, to determine what role they may play in the early assessment of hemophilic arthropathy in the future 63 (►Table 1).…”