Primary ventricular fibrillation in a patient with mild hypercalcemia

Marinheiro, Rita; Parreira, Leonor; Amador, Pedro; Sardinha, Francisco; Gonçalves, Sara; Serra, Sónia

doi:10.5935/abc.20180059

Cited by 2 publications

(1 citation statement)

References 11 publications

(15 reference statements)

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“…Low calcium can lead to circumoral or peripheral paranesthesia, tetany, carpopedal spasm, laryngospasm, and ECG changes from long QT interval to VT arrest [1,2]. While high calcium can cause fatigue, polyuria, polydipsia, nephrolithiasis, peptic ulcer disease, altered mental status, gait instability [3][4][5], myalgia, arthralgia, abdominal pain [4], rare submandibular gland atrophy and sialolithiasis, metastatic pulmonary calcification [6,7], sometimes even inducing acute kidney injury or acute pancreatitis [8][9][10][11][12][13], or being life-threatening [14,15]. The parathyroid gland is an adjacent organ of the thyroid.…”

Section: Introductionmentioning

confidence: 99%

Effect of Parathyroid Function After Thyroidectomy and Radioactive-Iodine Therapy for Thyroid Disease

Xiao¹,

Zhang²,

Li³

2019

BJSTR

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Objective: Thyroidectomy and radioactive-iodine (RAI) treatment are two important methods for benign and malignant thyroid diseases. Thyroidectomy and RAI treatment may influence parathyroid gland function. This paper systematically reviewed the literatures on the effect of thyroidectomy and RAI on parathyroid gland function in patients with benign and maligant thyroid disease. Subjective and Methods:We searched PubMed for English literautres by using terms of "thyroidectomy" or "radioactive iodine" and "hyperthyroidism" or "Graves' disease" or "toxic multinodular goiter" or "toxic adenoma" or "differentiated thyroid carcinoma" and "parathyroid gland" or "calcium" or "parathyroid hormone" to review the effect of thyroidectomy and RAI on parathyroid gland function.Result: Thyroidectomy may lead to hypocalcaemia and hypoparathyroidism both for benign thyroid disease and DTC. For benign thyroid disease, RAI treatment may cause increasing PTH in the short term and may induce parathyroid adenoma or hyperplasia in the long term. For DTC patients, parathyroid gland function may transiently decline after RAI treatment. Conclusion:Thyroidectomy and RAI treatment may influence the parathyroid function in both benign and DTC patients. Thus, it is important to monitor PTH and blood calcium regularly in order to detect early abnormal parathyroid function for those patients.

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Section: Introductionmentioning

confidence: 99%

Effect of Parathyroid Function After Thyroidectomy and Radioactive-Iodine Therapy for Thyroid Disease

Xiao¹,

Zhang²,

Li³

2019

BJSTR

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Excessive calcium consumption as a risk factor for cardiovascular diseases

Jandrić-Kočić¹,

Selmanovic²

2021

Timočki medicinski glasnik

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Calcium is the most abundant mineral in the human body that participates in the construction of bones and teeth, nerve impulse transmission, intracellular signaling, hormone secretion, muscle contraction, coagulation, ensuring normal heart rhythm and physiological values of blood pressure. Excessive calcium concentration, predominantly caused by improper use of supplements, predisposes to the development of cardiovascular disease. High serum calcium induces reprogramming and differentiation of smooth muscle cells into an osteoblast-like phenotype, translocation of prohypertrophic cardiomyocyte transcription factors, compromise of diastolic relaxation of the myocardium and necrosis of its contractile girdle, stimulation of coagulation reactions, stimulation of platelet aggregation, hemodynamic changes and metabolic abnormalities. Acute intoxication with calcium supplements results in an increase in blood pressure. Chronic consumption of excessive calcium concentration predisposes to atherosclerosis and calcification of blood vessels, heart attack and stroke, hypertrophy and heart failure, and heart rhythm disorders. There is a need to strengthen the response and role of the health system in informing the public about the side effects of excessive calcium consumption, limiting the widespread prescribing of supplements, as well as a possible comprehensive reassessment of the same.

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Primary ventricular fibrillation in a patient with mild hypercalcemia

Cited by 2 publications

References 11 publications

Effect of Parathyroid Function After Thyroidectomy and Radioactive-Iodine Therapy for Thyroid Disease

Effect of Parathyroid Function After Thyroidectomy and Radioactive-Iodine Therapy for Thyroid Disease

Excessive calcium consumption as a risk factor for cardiovascular diseases

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