Abstract:The relationship between sleep and pain was recently revisited by Whibley et al. 1 who aimed to provide additional evidence on the mutual interaction between those functional states of life. But something is missing, so we think. Sleep and pain lay down in common structural and functional matrixes. However, neither anatomical pathways or neurochemical substrates may entirely explain the complex interaction which subsides the physiopathology and clinical features of comorbid sleep impairment with acute or chron… Show more
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