Cardiorenal Syndrome Type 2: A Strong Prognostic Factor of Survival

Arous, S.; Benouna, Mohamed El Ghali; Mourid, M. El; Habbal, Rachida

doi:10.5935/2359-4802.20170072

Cited by 2 publications

(2 citation statements)

References 10 publications

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“…Hypertension and diabetes were much more prevalent among patients with Cardiorenal syndrome (CRS) compared to those without CRS, according to research [8]. More than 60 years of age, smoking, hypertension, coronary artery disease, diabetes, sepsis, and labs of blood urea, serum creatinine, eGFR, and LVEF were identified as death risk factors [9].…”

Section: Resultsmentioning

confidence: 99%

“…In their investigation, diabetes and uncontrolled hypertension were found as the two most important risk factors in patients with CRS. As demonstrated by the model developed by Kishimoto et al, it has been postulated that renal injury brought on by diabetes and/or hypertension and heart failure interacts with a connected and mutually reinforcing pathophysiology [8]. Hyperinsulinemia can reduce the quantity of uric acid excreted by the kidneys due to insulin's ability to stimulate the urate-anion exchanger and/ or sodium-dependent anion co-transporter in the brush border membranes of the renal proximal tubule and enhance urea reabsorption [30].…”

Section: Glycemic Controlmentioning

confidence: 99%

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Failure is not an Alternative: A Systematic Review of the Prognostic Factors of Cardiorenal Syndrome

Assefi¹,

Sharma²

2023

J Critical Care & Emerg Med

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Cardiorenal syndrome (CRS) is a pathophysiological condition of the heart and kidneys. Cardiac and renal illnesses are prevalent and commonly overlap to substantial increase mortality, morbidity, and cost. Smoking, hypertension, coronary artery disease, diabetes, sepsis, and labs of blood urea, serum creatinine, eGFR, and LVEF were identified as death risk factors. Up to 40% of decompensated HF patients exhibit with CRS 1. Just 9% of patients with acute HF had normal renal function. Those with type 4 CRS have a 49% higher mortality risk.

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Section: Resultsmentioning

confidence: 99%

Section: Glycemic Controlmentioning

confidence: 99%

Failure is not an Alternative: A Systematic Review of the Prognostic Factors of Cardiorenal Syndrome

Assefi¹,

Sharma²

2023

J Critical Care & Emerg Med

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Beyond the Cardiorenal Syndrome: Pathophysiological Approaches and Biomarkers for Renal and Cardiac Crosstalk

et al. 2022

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Cardiorenal syndrome encompasses complex multifactorial facets and carries significant morbidity and mortality worldwide. The bi-directional relationship between the heart and kidneys, where dysfunction in one organ worsens the function of the other, has been the leading motor for research in the last few years. In the pathophysiological process, small noncoding RNAs, epigenetics, vascular growth factors, oxidative stress, hemodynamic factors, and biomarkers play a pivotal role in the development of cardiorenal syndrome. It is therefore important to elucidate all the mechanisms in order to provide diagnostic and treatments tools. This review summarizes the hemodynamic and non-hemodynamic pathways along with biomarkers that could be the next target for diagnosis, treatment, and prognosis in cardiorenal syndrome.

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Cardiorenal Syndrome Type 2: A Strong Prognostic Factor of Survival

Cited by 2 publications

References 10 publications

Failure is not an Alternative: A Systematic Review of the Prognostic Factors of Cardiorenal Syndrome

Failure is not an Alternative: A Systematic Review of the Prognostic Factors of Cardiorenal Syndrome

Beyond the Cardiorenal Syndrome: Pathophysiological Approaches and Biomarkers for Renal and Cardiac Crosstalk

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