Effects of resistance exercise applied early after coronary artery bypass grafting: a randomized controlled trial

Ximenes, Nayana Nazaré Pessoa Sousa; Borges, Daniel Lago; Lima, Reijane Oliveira; Silva, Mayara Gabrielle Barbosa e; Silva, Luan Nascimento da; Costa, Maria do Rosário da Silva Ramos; Baldez, Thiago Eduardo Pereira; Nina, Vinicius José da Silva

doi:10.5935/1678-9741.20150077

Cited by 15 publications

(32 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Evidence supporting a beneficial effect of phase 1 cardiac rehabilitation after CABG is limited, and it is not well known when to start phase 1 rehabilitation after CABG. Previous small, randomized studies showed conflicting results of the effects of early rehabilitation within 3 days after CABG [ 17 , 18 , 19 , 20 , 21 ]. Rehabilitation too soon after CABG may increase the risk of coronary ischemia or inhibit wound healing [ 22 ].…”

Section: Introductionmentioning

confidence: 99%

Effect of Early Rehabilitation on Physical Function in Patients Undergoing Coronary Artery Bypass Grafting: A Nationwide Inpatient Database Study

Ohbe

Nakamura

Uda

et al. 2021

JCM

View full text Add to dashboard Cite

It is unclear when to begin rehabilitation after coronary artery bypass grafting (CABG) in the intensive care unit (ICU). Using the Japanese Diagnosis Procedure Combination inpatient database from 2010 to 2018, we identified adult patients who underwent a CABG and who were admitted to the ICU for ≥3 consecutive days from the date of their CABG. Patients who started any rehabilitation program prescribed by physicians or therapists within 3 days of CABG were defined as the early rehabilitation group, and the remaining patients were defined as the usual care group. We identified 30,568 eligible patients, with 13,150 (43%) patients in the early rehabilitation group. An inverse probability of treatment weighting analyses showed that the Barthel Index score at discharge in the early rehabilitation group was significantly higher than that in the usual care group (difference: 3.2; 95% confidence interval: 1.5–4.8). The early rehabilitation group had significantly lower in-hospital mortality, total hospitalization costs, length of ICU stay, and hospital stay vs. the usual care group. Our results suggested that early rehabilitation by physicians or therapists beginning within 3 days of CABG was safe, as suggested by the low mortality and improved physical function in patients who underwent CABG.

show abstract

Section: Introductionmentioning

confidence: 99%

Effect of Early Rehabilitation on Physical Function in Patients Undergoing Coronary Artery Bypass Grafting: A Nationwide Inpatient Database Study

Ohbe

Nakamura

Uda

et al. 2021

JCM

View full text Add to dashboard Cite

show abstract

“…In total, 70 trials with 3402 participants (mean age 54.6 years), were included in the data synthesis ( Table S1 ) 15–73 . These included six trials 18 , 38 , 41 in general surgery, three 34 , 54 , 59 in bariatric surgery, three 15 , 17 in breast cancer surgery, eleven 16 , 23 , 31 , 32 , 47 , 48 , 50 , 65 , 70 , 73 in cardiothoracic surgery, forty-one 19–21 , 24 , 26–30 , 33 , 35–37 , 39 , 40 , 43 , 45 , 49 , 51–53 , 55 , 57 , 58 , 60–64 , 66–69 , 71 , 72 in orthopaedics, three 42 , 44 , 46 in transplant surgery, one 56 in urology, one 25 in gynaecological surgery, and one 22 in trauma surgery. Some papers reported results of trial with multiple treatment arms: for the purpose of the meta-analysis, each treatment arm has been considered as a separate trial.…”

Section: Resultsmentioning

confidence: 99%

Interventions to prevent and treat sarcopenia in a surgical population: a systematic review and meta-analysis

2021

View full text Add to dashboard Cite

Background The aim of this systematic review was to summarize the results of trials evaluating interventions for the reduction of sarcopenia in patients undergoing surgery. Methods Searches were conducted using the Cochrane Central Register of Controlled Trials, MEDLINE and Embase. RCTs evaluating exercise, dietary or pharmacological interventions to address sarcopenia in the perioperative period were included. Treatment effect estimates were expressed as standardized mean differences (MDs) with confidence intervals, and heterogeneity was expressed as I2 values. Results Seventy trials including 3402 participants were selected for the data synthesis. Exercise interventions significantly increased muscle mass (MD 0.62, 95 per cent c.i. 0.34 to 0.90; P < 0.001), muscle strength (MD 0.55, 0.39 to 0.71; P < 0.001), measures of gait speed (MD 0.42, 0.05 to 0.79; P = 0.03), and reduced time for completion of set exercises (MD −0.76, −1.12 to −0.40; P < 0.001) compared with controls. Subgroup analysis showed that interventions in the early postoperative period were more likely to have a positive effect on muscle mass (MD 0.71, 0.35 to 1.07; P < 0.001) and timed tests (MD −0.70, −1.10 to −0.30; P = 0.005) than preoperative interventions. Treatment effects on muscle mass (MD 0.09, −0.31 to 0.49; P = 0.66) and strength (MD 0.46, −0.01 to 0.92; P = 0.05) were attenuated by the presence of cancer. Results of analyses restricted to nine trials at low risk of allocation concealment bias and fourteen trials at low risk of attrition bias were comparable to those of the primary analysis. Risk-of-bias assessment showed that most trials were at high risk of incomplete outcome and attrition bias, thus reducing the estimate of certainty of the evidence according to the GRADE assessment tool. Conclusion Exercise interventions appear beneficial in reducing the impact of sarcopenia. Because of the high risk of bias and low certainty of the current evidence, large RCTs using standardized measures of muscle mass should be undertaken.

show abstract

“…There is an increasing body of evidence that additional resistance exercises are safe and significantly improve functional capacity as well as increase muscle strength in patients with ischemic heart disease [ 20 ], chronic heart failure [ 21 ], and those who underwent CABG [ 22 ], and this is especially important for elderly patients.…”

Section: Discussionmentioning

confidence: 99%

Cardiac Rehabilitation and Complementary Physical Training in Elderly Patients after Acute Coronary Syndrome: A Pilot Study

et al. 2021

View full text Add to dashboard Cite

Background and Objectives: Nearly 23% of elderly patients hospitalized due to acute coronary syndrome have reduced muscle strength. It is assumed that these patients would better benefit from a complex training—a combination of endurance, strength, balance, coordination, and flexibility—in order to reduce the loss of muscle strength and mass and improve functional capacity. The aim of this study was to assess the effectiveness and safety of two different complementary resistance and balance training programs during short-term cardiac rehabilitation (CR) in elderly patients after a percutaneous or surgical intervention due to acute coronary syndrome. Materials and Methods: This randomized controlled trial was conducted from January 2020 to February 2021 in one Lithuanian rehabilitation hospital. A total of 63 participants who met the inclusion criteria were randomly assigned to three groups (at the ratio of 1:1:1): control (CG, n = 19), intervention 1 (IG-1, n = 26), and intervention 2 (IG-2, n = 18). All the patients attended a usual inpatient CR program of a mean duration of 18.7 ± 1.7 days, while the patients assigned to the intervention groups (IG-1 and IG-2) additionally received different resistance and balance training programs three days a week. Functional capacity, with 6-minute walk test (6MWT) and cardiopulmonary exercise testing (CPET), as well as physical performance, with the short physical performance battery (SPPB) test and one repetition maximum test (1RM) for leg press, were assessed at baseline and after CR. Results: The mean age of the participants was 72.9 ± 5.5 years; 73% were men. All parameters of functional capacity and physical performance improved significantly after CR (p < 0.05), except for peak VO2 that improved only in the IG-1. Comparison of CR effectiveness among the groups revealed no significant differences. Conclusions: All three rehabilitation programs were safe and well tolerated by elderly patients aged ≥65 years as well as improved functional capacity (6-minute walk distance and peak workload) and physical performance (SPPB and 1RM). Complementary resistance and balance training with traditional physical therapy means and exercises with mechanical devices did not show greater benefits for the results of physical performance compared with the usual CR program.

show abstract

Effects of resistance exercise applied early after coronary artery bypass grafting: a randomized controlled trial

Cited by 15 publications

References 15 publications

Effect of Early Rehabilitation on Physical Function in Patients Undergoing Coronary Artery Bypass Grafting: A Nationwide Inpatient Database Study

Effect of Early Rehabilitation on Physical Function in Patients Undergoing Coronary Artery Bypass Grafting: A Nationwide Inpatient Database Study

Interventions to prevent and treat sarcopenia in a surgical population: a systematic review and meta-analysis

Cardiac Rehabilitation and Complementary Physical Training in Elderly Patients after Acute Coronary Syndrome: A Pilot Study

Contact Info

Product

Resources

About