Primary gastric melanoma: a case report of a rare malignancy

Ferreira, Raquel Ida; Dentz, Leonardo Cunha; Assis, Emílio Augusto Campos Pereira de; Laboissiere, Renato Santos

doi:10.5935/1676-2444.20200034

Cited by 2 publications

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“…PGMM has been reported to occur in older patients with an average age of 71 years, often at an advanced stage, and is characterized by a worse prognosis [ 2 ] due to the tendency to grow faster and more aggressively than metastatic tumors, perhaps due to the rich lymphovascular supply available in the intestinal mucosa [ 6 ]. PGMM clinical manifestations are similar to other upper gastrointestinal (GI) lesions, such as weight loss, abdominal pain, anemia, nausea, and melaena due to GI bleeding [ 4 , 7 ]. Histologic diagnosis of melanoma requires the exclusion of metastasis from a primary cutaneous or ocular lesion, with full skin and eye examination by a dermatologist and an ophthalmologist, to rule out another primary source, as this influences both the prognosis and further management of the patient, including whether surgical resection is advisable [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Primary Gastric Malignant Melanoma

Kosmas

Vamvakaris

Psychogiou

et al. 2020

Cureus

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Primary gastric malignant melanoma (PGMM) is an extremely rare clinical entity, and few cases have been described in the literature. Here, we report a histologically confirmed PGMM case of a 74-year-old man with a mass in the stomach found by gastroscopy. The patient had no history of melanoma. This rare disease may be misdiagnosed for another gastric malignant tumor type when there is no known primary lesion. Early detection and surgical intervention are critical for long term survival or cure, though the tumor is often advanced at the time of diagnosis and is associated with a dismal outcome.

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